NUDT15 抗体
(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA.
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Latest Publications for our NUDT15 抗体
: "MutT-related proteins are novel progression and prognostic markers for colorectal cancer." in: Oncotarget, Vol. 8, Issue 62, pp. 105714-105726, (2017) (PubMed).Aliases for NUDT15 抗体
nudix hydrolase 15 (NUDT15) 抗体nudix (nucleoside diphosphate linked moiety X)-type motif 15 (Nudt15) 抗体
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