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NUDT15 产品

(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))

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Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA.

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Featured NUDT15 Categories

NUDT15 抗体

High quality antibodies with extensive validation data.

NUDT15 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NUDT15 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN6144931
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (5)
Cat. No. ABIN654983
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7264397
Quantity 200 μL
Datasheet Datasheet

Recommended NUDT15 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3084794
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3124647
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727746
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our NUDT15 Products

Li, Yang, Tian, Li, Cui, Chen, Deng, Chen, Hayakawa, Sekiguchi, Cai: "MutT-related proteins are novel progression and prognostic markers for colorectal cancer." in: Oncotarget, Vol. 8, Issue 62, pp. 105714-105726, (2017) (PubMed).

Synonyms and alternative names related to NUDT15

nudix hydrolase 15 (NUDT15), nudix (nucleoside diphosphate linked moiety X)-type motif 15 (Nudt15), 6530403O17, A730068G11Rik, MTH2, RP11-90M2.1

Protein level used designations for NUDT15

  • 7,8-dihydro-8-oxoguanine-triphosphatase NUDT15
  • 8-oxo-dGTPase NUDT15
  • A730068G11Rik
  • mutT homolog 2
  • nucleoside diphosphate-linked moiety X motif 15
  • nudix motif 15
  • nudix-type motif 15
  • probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15
  • probable 8-oxo-dGTP diphosphatase NUDT15
  • MutT homolog 2
  • mMTH2
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