NTRK3 抗体
(Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].
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Latest Publications for our NTRK3 抗体
: "Neurotrophin-3 restores synaptic plasticity in the striatum of a mouse model of Huntington's disease." in: CNS neuroscience & therapeutics, Vol. 24, Issue 4, pp. 353-363, (2018) (PubMed).: "A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth." in: Neuropharmacology, Vol. 110, Issue Pt A, pp. 343-61, (2016) (PubMed).
: "Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells." in: The Journal of biological chemistry, Vol. 290, Issue 6, pp. 3814-24, (2015) (PubMed).
: "Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes." in: Nature biotechnology, Vol. 33, Issue 1, pp. 89-96, (2015) (PubMed).
: "Neurotrophins regulate bone marrow stromal cell IL-6 expression through the MAPK pathway." in: PLoS ONE, Vol. 5, Issue 3, pp. e9690, (2010) (PubMed).
: "EGF and bFGF pre-treatment enhances neural specification and the response to neuronal commitment of MIAMI cells." in: Differentiation; research in biological diversity, Vol. 80, Issue 4-5, pp. 213-27, (2010) (PubMed).
: "BDNF mediated TrkB activation is a survival signal for transitional cell carcinoma cells." in: International journal of oncology, Vol. 36, Issue 6, pp. 1469-76, (2010) (PubMed).
: "TrkB antibody elicits cytotoxicity and suppresses migration/invasion of transitional cell carcinoma cells." in: International journal of oncology, Vol. 37, Issue 4, pp. 943-9, (2010) (PubMed).
: "A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin." in: The Journal of cell biology, Vol. 173, Issue 2, pp. 291-9, (2006) (PubMed).
: "Gene expression of TrkC (NTRK3) in human soft tissue tumours." in: The Journal of pathology, Vol. 197, Issue 5, pp. 661-7, (2002) (PubMed).
Aliases for NTRK3 抗体
neurotrophic receptor tyrosine kinase 3 (NTRK3) 抗体neurotrophic receptor tyrosine kinase 3 (Ntrk3) 抗体
neurotrophic tyrosine kinase, receptor, type 3 (Ntrk3) 抗体
AW125844 抗体
gp145(trkC) 抗体
Ntrk3_tv3 抗体
TRKC 抗体
trkC 抗体
TrkC 抗体
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