This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008].
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Aliases for NPPB 抗体
natriuretic peptide B (NPPB) 抗体 natriuretic peptide B (Nppb) 抗体 natriuretic peptide type B (Nppb) 抗体 AA408272 抗体 Bnf 抗体 BNP 抗体 BNP1 抗体 NPPB 抗体