This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
Li, Sun, Wang, Gao, Liu, Gao, Li, Zhang: "Dynamic expression pattern of neuro-oncological ventral antigen 1 (Nova1) in the rat brain after focal cerebral ischemia/reperfusion insults." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 61, Issue 1, pp. 45-54, (2012) (PubMed).
Jelen, Ule, Zivin: "Cholinergic regulation of striatal Nova mRNAs." in: Neuroscience, Vol. 169, Issue 2, pp. 619-27, (2010) (PubMed).
Jelen, Ule, Zivin, Darnell: "Evolution of Nova-dependent splicing regulation in the brain." in: PLoS genetics, Vol. 3, Issue 10, pp. 1838-47, (2007) (PubMed).
Aliases for NOVA1 抗体
NOVA alternative splicing regulator 1 (NOVA1) 抗体 NOVA alternative splicing regulator 1 (Nova1) 抗体 neuro-oncological ventral antigen 1 L homeolog (nova1.L) 抗体 neuro-oncological ventral antigen 1 (nova1) 抗体 neuro-oncological ventral antigen 1 (Nova1) 抗体 RNA-binding protein Nova-1 (LOC790874) 抗体 lipid A export ATP-binding/permease protein (novA1) 抗体 9430099M15Rik 抗体 G630039L02 抗体 Nova-1 抗体 NOVA1 抗体 si:ch211-222c22.9 抗体