The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009].
Perbal: "NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues." in: Molecular pathology : MP, Vol. 54, Issue 2, pp. 57-79, (2001) (PubMed).