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NOTCH3 抗体

(Notch 3 (NOTCH3))
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008].

Active filters:

  • 抗原: NOTCH3
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6835566
NOTCH3 抗体 (Alexa Fluor 594) NOTCH3 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6835565
NOTCH3 抗体 (Alexa Fluor 594) NOTCH3 · Primary Antibody 人 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN1737438
NOTCH3 抗体 (C-Term) NOTCH3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • 100 μg
发货至: 中国
ABIN7842002
NOTCH3 抗体 (C-Term) NOTCH3 · Primary Antibody 人 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • 200 μL
发货至: 中国
ABIN5903912
NOTCH3 抗体 (AA 47-156) NOTCH3 · Primary Antibody 人 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 100 μL
发货至: 中国
ABIN8123378
NOTCH3 抗体 (Cleaved-Asp1628) NOTCH3 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 50 μL
发货至: 中国
ABIN8123379
NOTCH3 抗体 (Cleaved-Val1662) NOTCH3 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 50 μL
发货至: 中国
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 594
产品编号 ABIN6835566
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 594
产品编号 ABIN6835565
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
C-Term
产品编号 ABIN1737438
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
抗原表位
C-Term
产品编号 ABIN7842002
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
抗体亚型
IgG2a
抗原表位
AA 47-156
产品编号 ABIN5903912
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
Cleaved-Asp1628
产品编号 ABIN8123378
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
Cleaved-Val1662
产品编号 ABIN8123379

Latest Publications for our NOTCH3 抗体

Diéguez-Hurtado, Kato, Giaimo, Nieminen-Kelhä, Arf, Ferrante, Bartkuhn, Zimmermann, Bixel, Eilken, Adams, Borggrefe, Vajkoczy, Adams: "Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes." in: Nature communications, Vol. 10, Issue 1, pp. 2817, (2019) (PubMed).

Kato, Diéguez-Hurtado, Park, Hong, Kato-Azuma, Adams, Stehling, Trappmann, Wrana, Koh, Adams: "Pulmonary pericytes regulate lung morphogenesis." in: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).

Zhang, Dong, Wang, Wang, Chen, Huang: "Involvement of Notch2 in all‑trans retinoic acid‑induced inhibition of mouse embryonic palate mesenchymal cell proliferation." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 2538-2546, (2017) (PubMed).

Liu, Yang, Wang, Miao, Liu, Li, Zou, Li, Liang, Zeng, Chen: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." in: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).

Zhou, Jiang, Dong, Yan, You, Su, Gong: "The proteins interacting with C-terminal of μ receptor are identified by bacterial two-hybrid system from brain cDNA library in morphine-dependent rats." in: Life sciences, Vol. 143, pp. 156-67, (2016) (PubMed).

Soylu, Acar, Ozbey, Unal, Koksal, Bassorgun, Ciftcioglu, Ustunel: "Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma." in: Pathology oncology research : POR, Vol. 22, Issue 1, pp. 87-94, (2015) (PubMed).

Soriani, Iannitto, Ricci, Fionda, Malgarini, Morrone, Peruzzi, Ricciardi, Petrucci, Cippitelli, Santoni: "Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 950-60, (2014) (PubMed).

Meng, Zhang, Lee, Wang: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).

Watanabe-Hosomi, Watanabe, Tanaka, Nakagawa, Mizuno: "Transendocytosis is impaired in CADASIL-mutant NOTCH3." in: Experimental neurology, Vol. 233, Issue 1, pp. 303-11, (2012) (PubMed).

Tada, Itoh, Ishii-Watabe, Suzuki, Kawasaki: "Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome." in: The FEBS journal, Vol. 279, Issue 12, pp. 2096-107, (2012) (PubMed).

Aliases for NOTCH3 抗体

notch 3 (NOTCH3) 抗体
notch 3 (Notch3) 抗体
notch 3 (notch3) 抗体
AW229011 抗体
CADASIL 抗体
CASIL 抗体
fa14b08 抗体
hpbk 抗体
IMF2 抗体
N3 抗体
notch5 抗体
wu:fa14b08 抗体
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