NOTCH3 抗体
(Notch 3 (NOTCH3))
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008].
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Latest Publications for our NOTCH3 抗体
: "Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes." in: Nature communications, Vol. 10, Issue 1, pp. 2817, (2019) (PubMed).: "Pulmonary pericytes regulate lung morphogenesis." in: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).
: "Involvement of Notch2 in all‑trans retinoic acid‑induced inhibition of mouse embryonic palate mesenchymal cell proliferation." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 2538-2546, (2017) (PubMed).
: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." in: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).
: "The proteins interacting with C-terminal of μ receptor are identified by bacterial two-hybrid system from brain cDNA library in morphine-dependent rats." in: Life sciences, Vol. 143, pp. 156-67, (2016) (PubMed).
: "Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma." in: Pathology oncology research : POR, Vol. 22, Issue 1, pp. 87-94, (2015) (PubMed).
: "Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 950-60, (2014) (PubMed).
: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).
: "Transendocytosis is impaired in CADASIL-mutant NOTCH3." in: Experimental neurology, Vol. 233, Issue 1, pp. 303-11, (2012) (PubMed).
: "Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome." in: The FEBS journal, Vol. 279, Issue 12, pp. 2096-107, (2012) (PubMed).
Aliases for NOTCH3 抗体
notch 3 (NOTCH3) 抗体notch 3 (Notch3) 抗体
notch 3 (notch3) 抗体
AW229011 抗体
CADASIL 抗体
CASIL 抗体
fa14b08 抗体
hpbk 抗体
IMF2 抗体
N3 抗体
notch5 抗体
wu:fa14b08 抗体
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