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NOTCH2 抗体

(Notch 2 (NOTCH2))
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].

93 results :

Rockland 100-401-408 NOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
Pubmed 3 references Independent Validation 1 validation
产品编号 ABIN104899
Independently Validated
NOTCH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3181821
 
NOTCH2 适用: 人, 小鼠 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN2854343
 
NOTCH2 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN680183
 
NOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7187531
 
NOTCH2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7161298
 
NOTCH2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7441634
 
NOTCH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6144736
 
NOTCH2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7187530
 
NOTCH2 适用: 人, 小鼠 FACS 宿主: 大鼠 Monoclonal 16F11 unconjugated
Pubmed 2 references
产品编号 ABIN1169006
 
NOTCH2 适用: 小鼠, 大鼠 FACS 宿主: 仓鼠 Monoclonal HMN2-35 unconjugated
Pubmed 3 references
产品编号 ABIN2475916
 
NOTCH2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN562026
 
NOTCH2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN960288
 
NOTCH2 适用: 人, 小鼠, 犬, 猴, Pig, Cow, Bat WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6742309
 
NOTCH2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3181820
 
NOTCH2 适用: 人, 小鼠 ELISA, IF, BP 宿主: 兔 Chimeric B6 unconjugated Recombinant Antibody
产品编号 ABIN5668275
 
NOTCH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1536095
 
NOTCH2 适用: 人, 小鼠, 大鼠, 犬, Pig, 兔, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN2777549
 
NOTCH2 适用: 小鼠, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6989318
 
NOTCH2 适用: 小鼠, 大鼠 ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN6982812
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Flow Cytometry (FACS)
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunocytochemistry (ICC)
    • Blocking Peptide (BP)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • ChIP DNA-Sequencing (ChIP-seq)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Mouse
    • Rat
    • Pig
    • Dog
    • Monkey
    • Cow
    • Rabbit
    • Bat
    • Chimpanzee
    • Guinea Pig
    • Horse
  • 论文引用
  • 图像
  • 独立验证
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Rat
    • Hamster
    • Goat
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
    • Chimeric
  • 克隆
    • B6
    • 16F11
    • HMN2-35
    • 2D1B2
    • 4C5A8
    • 59R1
    • NOD-15
    • PT0367R
  • 抗原表位
    • AA 1871-1970
    • AA 1501-1700
    • AA 59-250
    • AA 2421-2471
    • Cleaved-Ala1734
    • AA 1391-1677
    • AA 2250-2300
    • AA 2251-2466
    • Asp1733
    • C-Term
    • Cleaved-Asp1733
    • Cleaved-Val1697
    • Internal Region
    • cleaved
    • AA 1550-1600
    • AA 1678-1727
    • AA 1684-1733
    • AA 1715-1764
    • AA 2063-2413
    • AA 2194-2471
    • AA 2242-2471
    • AA 2376-2425
    • AA 2396-2409
    • AA 27-136
    • Asp1732
    • Middle Region
    • N-Term
    • Val1697
    • Val2332
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • PE
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • PE-Cy5
    • PE-Cy5.5
    • PE-Cy7
  • 抗体亚型
    • IgG
    • IgG1
    • IgG2a
    • kappa
    • IgG kappa
    • IgG1 kappa
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Recent
  • Supplier
    • antibodies-online
    • Signalway
    • Assay Biotechnology Company, Inc.
    • Abbexa
    • Biomatik
    • Covalab
    • Aviva Systems Biology
    • Boster Bio
    • Enogene Biotech
    • ProSci
    • Rockland

Latest Publications for our NOTCH2 抗体

Iervolino, Prosperi, De La Motte, Petrillo, Spagnuolo, DAcierno, Siccardi, Perna, Christensen, Frische, Capasso, Trepiccione: "Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway." in: Scientific reports, Vol. 10, Issue 1, pp. 5708, (2020) (PubMed).

Blancas, Medina-Berlanga, Ortíz-García, Loredo-Ramírez, Santos: "Protein Expression Analysis in Uterine Cervical Cancer for Potential Targets in Treatment." in: Pathology oncology research : POR, (2018) (PubMed).

Lin, Xie, Lin, Fu, Su, Tong, Chen, Wang, Zhao, Xia, Zhang, Zhang: "Epistatic Association of CD14 and NOTCH2 Genetic Polymorphisms with Biliary Atresia in a Southern Chinese Population." in: Molecular therapy. Nucleic acids, Vol. 13, pp. 590-595, (2018) (PubMed).

Shiina, Nakayama: "RNA granule assembly and disassembly modulated by nuclear factor associated with double-stranded RNA 2 and nuclear factor 45." in: The Journal of biological chemistry, Vol. 289, Issue 30, pp. 21163-80, (2015) (PubMed).

Saint-Geniez, Ghelfi, Liang, Yu, Spencer, Abend, Hotamisligil, Cataltepe: "Fatty acid binding protein 4 deficiency protects against oxygen-induced retinopathy in mice." in: PLoS ONE, Vol. 9, Issue 5, pp. e96253, (2015) (PubMed).

Yu, Qi, Feng, Zhang, Zhang, Tian: "Interference of Notch 2 inhibits the progression of gliomas and induces cell apoptosis by induction of the cell cycle at the G0/G1 phase." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 734-8, (2014) (PubMed).

Geng, Lan, Singha, Gilchrist, Weinreb, Violette, Weinberg, Saikumar, Venkatachalam: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).

Gibb, El Shikh, Kang, Rowe, El Sayed, Cichy, Yagita, Tew, Dempsey, Crawford, Conrad: "ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo." in: The Journal of experimental medicine, Vol. 207, Issue 3, pp. 623-35, (2010) (PubMed).

Siar, Ha, Aung, Nakano, Tsujigiwa, Nagatsuka, Ng, Kawakami: "Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor." in: European journal of medical research, Vol. 15, Issue 10, pp. 456-60, (2010) (PubMed).

Siar, Nagatsuka, Chuah, Rivera, Nakano, Ng, Kawakami: "Notch4 overexpression in ameloblastoma correlates with the solid/multicystic phenotype." in: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, Vol. 110, Issue 2, pp. 224-33, (2010) (PubMed).

Aliases for NOTCH2 抗体

neurogenic locus notch homolog protein 2 (LOC581186) 抗体
notch 2 (NOTCH2) 抗体
notch 3 (notch3) 抗体
notch 2 (Notch2) 抗体
notch 2 (notch2) 抗体
AGS2 抗体
AI853703 抗体
HJCYS 抗体
hN2 抗体
N2 抗体
notch6 抗体
sb:cb884 抗体
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