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NFE4 产品

(Transcription Factor NF-E4 (NFE4))

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The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008].

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Featured NFE4 Categories

NFE4 抗体

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to NFE4

nuclear factor, erythroid 4 (NFE4), NF-E4

Protein level used designations for NFE4

  • fetal globin activator NF-E4
  • gamma-globin gene activator
  • transcription factor NF-E4
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