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抗Mouse (Murine) IL1B 抗体:
抗Rat (Rattus) IL1B 抗体:
抗Human IL1B 抗体:
Human Monoclonal IL1B Primary Antibody for CyTOF, FACS - ABIN4899224
Yates, Burgess, Kocsis-Angle, Antal, Dority, Embury, Piotrkowski, Brunden: Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. in Journal of neurochemistry 2000
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Human Monoclonal IL1B Primary Antibody for CyTOF, FACS - ABIN4899223
Oliver, Lovric, Yu, Christou, Aiken, Cooper, Walsh: Development of a Novel Model for the Assessment of Dead-Space Management in Soft Tissue. in PLoS ONE 2015
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Bacteria Polyclonal IL1B Primary Antibody for ELISA, EM - ABIN269770
Petrovski, Ayna, Majai, Hodrea, Benko, Mádi, Fésüs: Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages. in Autophagy 2011
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Dog (Canine) Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN728503
Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011
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Dog (Canine) Polyclonal IL1B Primary Antibody for IHC, ELISA - ABIN1582289
Choi, Lim, Hwang, Lee, Cho, Kim: Anti-ischemic and anti-inflammatory activity of (S)-cis-verbenol. in Free radical research 2010
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Mouse (Murine) Polyclonal IL1B Primary Antibody for Neut, WB - ABIN223538
Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. in Journal of immunology (Baltimore, Md. : 1950) 2006
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Human Polyclonal IL1B Primary Antibody for IHC (p), IHC - ABIN446969
Omran, Peng, Zhang, Xiang, Xue, Gan, Kong, Yin: Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy. in Epilepsia 2012
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Mouse (Murine) Monoclonal IL1B Primary Antibody for IP, Neut - ABIN1176987
Fei, Gott, Edwards, Schuyler: Experimental hypersensitivity pneumonitis: in vitro effects of interleukin-2 and interferon-gamma. in The Journal of laboratory and clinical medicine 1995
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Mouse (Murine) Polyclonal IL1B Primary Antibody for ELISA, FACS - ABIN4324365
Triantafilou, Kar, Vakakis, Kotecha, Triantafilou: Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation. in Thorax 2012
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Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895764
Hakonarson, Whelan, Leiter, Kim, Chen, Campbell, Grunstein: T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. in The Journal of allergy and clinical immunology 2002
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This study reveals that proper levels of Il1b signaling and tissue inflammation, which are tuned by macrophages, play a crucial role in tissue regeneration.
Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (显示 CASP3 抗体) dependent manner.
Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.
findings reveal that the Il-1beta-Myd88 (显示 MYD88 抗体) axis and NADPH oxidase (显示 NOX1 抗体)-mediated ROS (显示 ROS1 抗体) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.
the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae
These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.
Alendronate (ALN (显示 TTC21B 抗体))-augmented IL-1beta production and cell death require Smad3 (显示 SMAD3 抗体) and ASC (显示 STS 抗体) activation, and SIS3 and anti-ASC (显示 STS 抗体) antibodies may serve as palliative agents for necrotizing inflammatory diseases caused by ALN (显示 TTC21B 抗体)
urinary LRG (显示 LRG1 抗体) is produced in renal tubular epithelial cells by interleukin-1beta (IL-1beta) that is released during proteinuria-induced renal damage
These data reveal how, upon XIAP (显示 XIAP 抗体) deficiency, a TLR-TNF (显示 TNF 抗体)-TNFR2 (显示 TNFRSF1B 抗体) axis drives cIAP1 (显示 BIRC2 抗体)-TRAF2 (显示 TRAF2 抗体) degradation to allow TLR or TNFR1 (显示 TNFRSF1A 抗体) activation of RIPK3 (显示 RIPK3 抗体)-caspase-8 (显示 CASP8 抗体) and IL-1beta. This mechanism may explain why XIAP (显示 XIAP 抗体)-deficient patients can exhibit symptoms reminiscent of patients with activating inflammasome mutations.
IL-1beta exerts variable effects on long-term potentiation at different kinds of synapses, indicating that IL-1beta has synapse-specific effects on hippocampal synaptic plasticity.
we assessed the role of RIP3 (显示 MPRIP 抗体) in synergy with Caspase-1 (显示 CASP1 抗体) in the induction of IL-1beta production in BMDM after either LPS (显示 TLR4 抗体)/ATP or Chlamydia muridarum stimulation. The possibility of pyroptosis and necroptosis interplays and the role of RIP3 (显示 MPRIP 抗体) in IL-1beta production during Chlamydia muridarum infection in BMDM was investigated as well.
Inhibition of signaling stimulated by both TNF (显示 TNF 抗体) and IL1beta synergizes with NF-kappaB (显示 NFKB1 抗体) inhibition in eliminating leukemic stem cells.
Parenchymal polymorphonuclear myeloid-derived suppressor cell (PMN (显示 TBCE 抗体)-MDSC), have a positive correlation with IL1a (显示 IL1A 抗体), IL8 (显示 IL8 抗体), CXCL5 (显示 CXCL5 抗体), and Mip-1a (显示 CCL3 抗体), suggesting they may attract PMN (显示 TBCE 抗体)-MDSC into the tumor
Chemokine receptor 2 (CCR2 (显示 CCR2 抗体)(+)) monocytes invade the hippocampus between 1 and 3 d after SE. In contrast, only an occasional CD3 (显示 CD3E 抗体)(+) T lymphocyte was encountered 3 d after SE. The initial cellular sources of the chemokine (显示 CCL1 抗体) CCL2 (显示 CCL2 抗体), a ligand for CCR2 (显示 CCR2 抗体), included perivascular macrophages and microglia. The induction of the proinflammatory cytokine IL-1beta was greater in FACS-isolated microglia than in brain-invading monocytes
hypernociception in experimental model of autoimmune encephalomyelitis may be a consequence of the increase in some cytokines in dorsal root ganglia, especially IL-1beta.
An OA model was established in mouse articular chondrocytes (MACs) treated by interleukin-1beta (IL-1beta).
This study demonstrated that IL1B expression levels are related to major depressive disorder and conjunctly mediate the effect of childhood maltreatment history on the risk of developing major depressive disorder.
GDNF has a role in lower than expected motor development, but while IL-1beta and CXCL8/IL-8 (显示 IL8 抗体) values were higher in the group with typical motor development among preterm neonates
Our findings call into question the role of IL-1beta in the diabetic pancreas as it has been proposed in previous literature. Additionally, our results regarding the localization of IL-1beta should lead to further investigation into the role of IL-1beta in the physiology of pancreatic alpha cells.
IL-1beta rs1143627 polymorphism is not related to periodontal disease susceptibility in the overall population based on the current evidence.
Our results do not show any evidence of association between COPD (显示 ARCN1 抗体) and IL-1beta -511 and +3954 gene polymorphisms in Turkish population
Our findings suggest that AhR (显示 AHR 抗体)-mediated IL-1beta regulation in cerebral endothelium could induce BBB (显示 ALMS1 抗体) breakdown and contribute to the pathogenesis of a variety of neurologic disorders.
the IL1B -511 T > C polymorphism may serve as important risk factor for recurrent miscarriage while the IL6 (显示 IL6 抗体) -634C > G polymorphism may protect against the risk of recurrent miscarriage
Our data suggests that the polymorphism in genes IL-1beta, IL-1Ra (显示 IL1RN 抗体) and FABP1 (显示 FABP1 抗体) included in this study are not associated with PCOS development, but can influence important biochemical and metabolic parameters in PCOS.
both RAGE (显示 AGER 抗体) and mitochondrial damage primed NLRP3 (显示 NLRP3 抗体) and pro-IL-1beta activation as upstream signals of NF-kappaB (显示 NFKB1 抗体) activity, whereas mitochondrial damage was critical for the assembly of inflammasome components. These results revealed that accumulation of AGEs in NP tissue may initiate inflammation-related degeneration of the intervertebral disc via activation of the NLRP3 (显示 NLRP3 抗体) inflammasome.
Here, the authors used a set of isogenic streptococcal NAD(+)-glycohydrolase mutants and a macrophage infection model and report that streptococcal streptococcal NAD(+)-glycohydrolase inhibits the innate immune response by decreasing inflammasome-dependent interleukin 1beta (IL-1beta) release from infected macrophages.
This study showed that the presence of embryos in oviducts on days 2-3 after mating may influence the oviductal expression of the members of the IL-1beta system, determining the action of IL-1beta, which may be considered to be the earliest sign of pregnancy in pigs.
This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.
local expression of IL-1beta and IL-8 (显示 IL8 抗体) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls
IL1B regulates expression of IL1R1 (显示 IL1RN 抗体) and IL1RAP (显示 IL1RAP 抗体) and stimulates expression of PTGS1 (显示 PTGS1 抗体) and PTGS2 (显示 PTGS2 抗体) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (显示 PLIN1 抗体)-implantation period of pregnancy in pigs.
the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.
Mycobacterium bovis infected animals have a higher frequency of IFN-gamma (显示 IFNG 抗体) producing CD4 (显示 CD4 抗体)(+) T cells and elevated plasma IL-1beta levels.
The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (显示 IL1RN 抗体) protein and IL1B and IL1R1 (显示 IL1RN 抗体) mRNA were detected.
For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (显示 P2RX7 抗体).
Role of TGF-beta1 (显示 TGFB1 抗体) and TNF-alpha (显示 TNF 抗体) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Testicular IL-1 alpha (显示 IL1A 抗体) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (显示 IL1A 抗体) bioactivity and IL-6 (显示 IL6 抗体) concentrations were greatest in the immediate pre-pubertal period.
Data describe the expression of IL-8 (显示 IL8 抗体), IL-1beta and their respective receptors, CXCR1 (显示 CXCR1 抗体) and IL-1R1 in bovine theca cells, and suggest that VEGF (显示 VEGFA 抗体) is associated with the IL system in theca cells in ovary.
Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (显示 PGF 抗体)(2alpha) and PGE (显示 LIPF 抗体)(2) production during luteal phase.
non-metalloproteinase mechanisms participate in IL-1 (显示 IL1A 抗体)-induced matrix degradation and loss of tissue material properties
dynamic compression stimulates cell proliferation and proteoglycan (显示 Vcan 抗体) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (显示 JUN 抗体) signalling pathways
These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (显示 TNF 抗体) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.
Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (显示 IL6 抗体) in rabbit cornea cells.
IL-1beta and TNF-alpha (显示 TNF 抗体) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (显示 TNF 抗体).
IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (显示 SLC2A5 抗体) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.
The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.
Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (显示 TGFB1 抗体), which delays the development of osteoarthritis.
In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.
results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (显示 COX2 抗体), and TGFbeta1 (显示 TGFB1 抗体)
Increased PGE2 production led to reduction in 5-LO (显示 ALOX5 抗体) products in LPS (显示 IRF6 抗体)-treated equine whole blood via IL-1b.
Results suggested that chemokine (显示 CCL1 抗体) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.
IL-1beta-induced up-regulation of matrix metalloproteinase 13 (显示 MMP13 抗体) mRNA was blocked by all concentrations of geldanamycin tested
This study examined effects of in vitro exposure to solutions of hay (显示 GTF2H5 抗体) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
, IL-1 beta
, interleukin-1 beta
, preinterleukin 1 beta
, prointerleukin-1 beta
, Interleukin-1 beta
, precursor interleukin-1beta
, interleukin-1 beta proprotein
, interleukin 1 beta
, lymphocyte proliferation-potentiating factor