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IKZF3 抗体

(IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012].
IKZF3 抗体 IKZF3 抗体 IKZF3 抗体 (ABIN7267842)

IKZF3 适用: 人 IF, IHC, WB 宿主: 兔 Monoclonal unconjugated

IKZF3 抗体  (N-Term) IKZF3 抗体  (N-Term) IKZF3 抗体 (N-Term) (ABIN2780886)

IKZF3 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔 IHC, WB 宿主: 兔 Polyclonal unconjugated

IKZF3 抗体  (AA 1-509) IKZF3 抗体  (AA 1-509) IKZF3 抗体 (AA 1-509) (ABIN564938)

IKZF3 适用: 人 IF, ELISA, WB 宿主: 小鼠 Monoclonal 3H5-G7 unconjugated

IKZF3 抗体 by 适用

Find IKZF3 抗体 for a variety of species such as anti-Human IKZF3, anti-Mouse IKZF3, anti-Cow IKZF3. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find IKZF3 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find IKZF3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Find IKZF3 抗体 with a specific conjugate such as PE, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular IKZF3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (7)
Cat. No. ABIN7267842
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
Application IHC, WB
Validations
  • (3)
Cat. No. ABIN2780886
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (1)
  • (2)
Cat. No. ABIN564938
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (3)
Cat. No. ABIN524769
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7129834
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, ICC, IF, WB
Validations
  • (2)
Cat. No. ABIN6258240
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7236301
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN6749714
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN927758
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7187027
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7176569
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN3180687
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6737865
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF
Validations
  • (1)
Cat. No. ABIN7263283
Quantity 200 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Dog, Human, Mouse, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN927759
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our IKZF3 抗体

Zhu, Shi, Bruins, Wang, Riggs, Porter, Ahmann, de Campos, Braggio, Bergsagel, Stewart: "Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4." in: Blood cancer journal, Vol. 9, Issue 2, pp. 19, (2019) (PubMed).

Kinoshita, Ri, Kanamori, Aoki, Yoshida, Narita, Totani, Ito, Kusumoto, Ishida, Komatsu, Iida: "Potent antitumor effect of combination therapy with sub-optimal doses of Akt inhibitors and pomalidomide plus dexamethasone in multiple myeloma." in: Oncology letters, Vol. 15, Issue 6, pp. 9450-9456, (2018) (PubMed).

Nguyen, Li, Lu, Mamrosh, Lu, Cathers, Deshaies: "p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 14, pp. 3565-3571, (2017) (PubMed).

Gao, Geng, Song, Lin, Liu, Cai, Cang: "Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase." in: The Journal of biological chemistry, Vol. 292, Issue 9, pp. 3683-3691, (2017) (PubMed).

Uehara, Minoshima, Sagane, Sugi, Mitsuhashi, Yamamoto, Kamiyama, Takahashi, Kotake, Uesugi, Yokoi, Inoue, Yoshida, Mabuchi, Tanaka, Owa: "Selective degradation of splicing factor CAPERα by anticancer sulfonamides." in: Nature chemical biology, Vol. 13, Issue 6, pp. 675-680, (2017) (PubMed).

Costa, Vescovini, Bolzoni, Marchica, Storti, Toscani, Accardi, Notarfranchi, Dalla Palma, Manferdini, Manni, Todaro, Lisignoli, Piazza, Aversa, Giuliani: "Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties." in: Oncotarget, Vol. 8, Issue 32, pp. 53053-53067, (2017) (PubMed).

Zhu, Braggio, Shi, Kortuem, Bruins, Schmidt, Chang, Langlais, Luo, Jedlowski, LaPlant, Laumann, Fonseca, Bergsagel, Mikhael, Lacy, Champion, Stewart: "Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma." in: Blood, Vol. 124, Issue 4, pp. 536-45, (2014) (PubMed).

Matulic, Paradzik, Cicin-Sain, Kapitanovic, Dubravcic, Batinic, Antica: "Ikaros family transcription factors in chronic and acute leukemia." in: American journal of hematology, Vol. 84, Issue 6, pp. 375-7, (2009) (PubMed).

Thompson, Cobb, Sabbattini, Meixlsperger, Parelho, Liberg, Taylor, Dillon, Georgopoulos, Jumaa, Smale, Fisher, Merkenschlager: "Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits." in: Immunity, Vol. 26, Issue 3, pp. 335-44, (2007) (PubMed).

Aliases for IKZF3 抗体

IKAROS family zinc finger 3 (IKZF3) 抗体
IKAROS family zinc finger 3 L homeolog (ikzf3.L) 抗体
IKAROS family zinc finger 3 (Ikzf3) 抗体
5830411O07Rik 抗体
AIO 抗体
aio 抗体
AIOLOS 抗体
aiolos 抗体
Aiolos 抗体
IKZF3 抗体
Zfpn1a3 抗体
ZNFN1A3 抗体
znfn1a3 抗体
Znfn1a3 抗体
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