NCOR2 抗体
(Nuclear Receptor Co-Repressor 2 (NCOR2))
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011].
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45 results
NCOR2
适用: 人, 猴
WB, IHC, IP, IHC (fro), ChIP
宿主: 小鼠
Monoclonal
1212
unconjugated
KO Validated
NCOR2
适用: 人
WB, IP, IHC (fro), ChIP
宿主: 小鼠
Monoclonal
1212
unconjugated
Latest Publications for our NCOR2 抗体
: "SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ER? transcriptional activity." in: Cancer research, Vol. 73, Issue 1, pp. 246-55, (2013) (PubMed).: "miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene." in: PLoS ONE, Vol. 7, Issue 1, pp. e30772, (2012) (PubMed).
: "In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer." in: The American journal of pathology, Vol. 179, Issue 2, pp. 1030-40, (2011) (PubMed).
: "Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 5052-61, (2003) (PubMed).
: "Repressors of androgen and progesterone receptor action." in: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 31136-48, (2003) (PubMed).
: "SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24177-85, (2001) (PubMed).
: "Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway." in: Genes & development, Vol. 14, Issue 1, pp. 45-54, (2000) (PubMed).
: "Unique forms of human and mouse nuclear receptor corepressor SMRT." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 6, pp. 2639-44, (1999) (PubMed).
: "The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor." in: Molecular and cellular biology, Vol. 18, Issue 3, pp. 1369-78, (1998) (PubMed).
: "Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase." in: Cell, Vol. 89, Issue 3, pp. 373-80, (1997) (PubMed).
Aliases for NCOR2 抗体
nuclear receptor corepressor 2 (NCOR2) 抗体nuclear receptor co-repressor 2 (Ncor2) 抗体
nuclear receptor corepressor 2 (ncor2) 抗体
nuclear receptor co-repressor 2 (NCOR2) 抗体
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