Myc Proto-Oncogene protein 蛋白
(Myc Proto-Oncogene protein (MYC))
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].
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32 results
MYC
宿主: 人
宿主: 小麦胚
Recombinant
ELISA, WB, AP, AA
1 image
2 references
MYC
宿主: 人
宿主: 小麦胚
Recombinant
ELISA, WB, AP, AA
1 image
1 reference
MYC
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
14 references
MYC
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % as determined by SDS-PAGE
ELISA, WB
1 image
MYC
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90% as determined by SDS-PAGE.
ELISA, SDS
1 image
3 references
MYC
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS
1 image
Latest Publications for our Myc Proto-Oncogene protein 蛋白
: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." in: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).: "USP7 is essential for maintaining Rad18 stability and DNA damage tolerance." in: Oncogene, Vol. 35, Issue 8, pp. 965-76, (2016) (PubMed).
: "NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells." in: Biochemical and biophysical research communications, Vol. 461, Issue 3, pp. 501-6, (2015) (PubMed).
: "Reversible linkage of two distinct small molecule inhibitors of Myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines." in: PLoS ONE, Vol. 10, Issue 4, pp. e0121793, (2015) (PubMed).
: "Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming." in: Cell, Vol. 161, Issue 3, pp. 555-68, (2015) (PubMed).
: "Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation." in: The Journal of clinical investigation, Vol. 125, Issue 3, pp. 1098-110, (2015) (PubMed).
: "Anti-signal recognition particle autoantibody ELISA validation and clinical associations." in: Rheumatology (Oxford, England), Vol. 54, Issue 7, pp. 1194-9, (2015) (PubMed).
: "L-Plastin S-glutathionylation promotes reduced binding to β-actin and affects neutrophil functions." in: Free radical biology & medicine, Vol. 86, pp. 1-15, (2015) (PubMed).
: "The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 35, Issue 9, pp. 720-33, (2015) (PubMed).
: "Profiles of hypothalamus-pituitary-interrenal axis gene expression in the parr and smolt stages of rainbow trout, Oncorhynchus mykiss: effects of recombinant aquaporin 3 and seawater acclimation." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 182, pp. 14-21, (2015) (PubMed).
Aliases for Myc Proto-Oncogene protein 蛋白
MYC proto-oncogene, bHLH transcription factor (MYC) 蛋白v-myc myelocytomatosis viral oncogene homolog (LOC100136746) 蛋白
nucleolar protein 3 (apoptosis repressor with CARD domain) (Nol3) 蛋白
MYC proto-oncogene, bHLH transcription factor (Myc) 蛋白
myelocytomatosis oncogene (Myc) 蛋白
MYC proto-oncogene, bHLH transcription factor a (myca) 蛋白
MYC proto-oncogene, bHLH transcription factor L homeolog (myc.L) 蛋白
MYC proto-oncogene, bHLH transcription factor S homeolog (myc.S) 蛋白
v-myc myelocytomatosis viral oncogene homolog (avian) (MYC) 蛋白
MYC proto-oncogene, bHLH transcription factor b (mycb) 蛋白
CG10798 gene product from transcript CG10798-RB (Myc) 蛋白
anon-WO03040301.171 蛋白
ARC 蛋白
AU016757 蛋白
B430311C09Rik 蛋白
bHLHe39 蛋白
bHLHe57 蛋白
c-Myc 蛋白
c-myc 蛋白
C-MYC 蛋白
c-MYC 蛋白
c-myc II 蛋白
CG10798 蛋白
CMYC 蛋白
cmyc 蛋白
CMyc 蛋白
D-Myc 蛋白
d-myc 蛋白
da 蛋白
DM 蛋白
Dm 蛋白
dm 蛋白
dm/dMyc 蛋白
dm/myc 蛋白
Dmel\CG10798 蛋白
DMYc 蛋白
Dmyc 蛋白
dMYC 蛋白
dMyc 蛋白
dmyc 蛋白
dMyc1 蛋白
dmyc1 蛋白
EG:BACN5I9.1 蛋白
l(1)G0139 蛋白
l(1)G0354 蛋白
l(1)G0359 蛋白
LOC100136746 蛋白
mMyc 蛋白
MRTL 蛋白
MYC 蛋白
myc 蛋白
myc-B 蛋白
myc1 蛋白
Myc2 蛋白
myc2 蛋白
MYCC 蛋白
Niard 蛋白
Nird 蛋白
NOP 蛋白
Nop30 蛋白
RNCMYC 蛋白
zc-myc 蛋白
zgc:55680 蛋白
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