MYCN 蛋白
(N-Myc Proto-Oncogene Protein (MYCN))
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| MYCN Protein (AA 1-464) (GST tag) | 人 | 小麦胚 |
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| MYCN Protein (AA 282-464) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| MYCN Protein (AA 1-100) (GST tag) | 人 | 小麦胚 |
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| MYCN Protein (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| MYCN Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
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| MYCN Protein (AA 1-464) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| MYCN Protein (AA 1-462) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| MYCN Protein (AA 1-464, full length) | 人 | Baculovirus infected Insect Cells |
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| MYCN Protein (AA 1-427) (His tag) | Serinus canaria | 酵母菌 |
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| MYCN Protein (AA 1-441) (His tag) | 小鸡 | 酵母菌 |
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| MYCN Protein (His-SUMO Tag,Strep Tag) | 人 | 大肠杆菌（E. Coli） |
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| MYCN Protein (AA 48-138) (His-SUMO Tag,Strep Tag) | 人 | Bacteria |
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Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
4 references - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Serinus canaria
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 小鸡
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our MYCN 蛋白
: "P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma." in: Molecular & cellular proteomics : MCP, Vol. 22, Issue 3, pp. 100504, (2023) (PubMed).
: "Novel pharmacodynamic biomarkers for MYCN protein and PI3K/AKT/mTOR pathway signaling in children with neuroblastoma." in: Molecular oncology, (2015) (PubMed).
: "NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3? resulting in the stabilization of MYCN in human neuroblastomas." in: PLoS genetics, Vol. 10, Issue 1, pp. e1003996, (2014) (PubMed).
: "A matrix approach to guide IHC-based tissue biomarker development in oncology drug discovery." in: The Journal of pathology, Vol. 232, Issue 2, pp. 190-8, (2013) (PubMed).
: "Novel pharmacodynamic biomarkers for MYCN protein and PI3K/AKT/mTOR pathway signaling in children with neuroblastoma." in: Molecular oncology, (2015) (PubMed).
: "NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3? resulting in the stabilization of MYCN in human neuroblastomas." in: PLoS genetics, Vol. 10, Issue 1, pp. e1003996, (2014) (PubMed).
: "A matrix approach to guide IHC-based tissue biomarker development in oncology drug discovery." in: The Journal of pathology, Vol. 232, Issue 2, pp. 190-8, (2013) (PubMed).
Aliases for MYCN 蛋白
MYCN proto-oncogene, bHLH transcription factor (MYCN) 蛋白v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN) 蛋白
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (Mycn) 蛋白
MYCN proto-oncogene, bHLH transcription factor (Mycn) 蛋白
olfactory receptor 8S1 (LOC515887) 蛋白
MYCN proto-oncogene, bHLH transcription factor (mycn) 蛋白
MYCN proto-oncogene, bHLH transcription factor S homeolog (mycn.S) 蛋白
bHLHe37 蛋白
c-nmyc 蛋白
fb57a02 蛋白
MODED 蛋白
mycn 蛋白
mycn-a 蛋白
mycn-b 蛋白
mycna 蛋白
MYCNOT 蛋白
N-myc 蛋白
Nmuc1 蛋白
NMYC 蛋白
Nmyc 蛋白
Nmyc-1 蛋白
Nmyc1 蛋白
nmyc1 蛋白
ODED 蛋白
wu:fb57a02 蛋白
XN-myc 蛋白
xN-myc1 蛋白
XNmyc 蛋白
zgc:85706 蛋白
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