MVB12B 蛋白
(Multivesicular Body Subunit 12B (MVB12B))
The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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custom-made
MVB12B
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MVB12B
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for MVB12B 蛋白
multivesicular body subunit 12B (MVB12B) 蛋白multivesicular body subunit 12B (Mvb12b) 蛋白
multivesicular body subunit 12B S homeolog (mvb12b.S) 蛋白
multivesicular body subunit 12Ba (mvb12ba) 蛋白
2610200O14Rik 蛋白
2610528K11Rik 蛋白
AI414895 蛋白
C9orf28 蛋白
FAM125B 蛋白
Fam125b 蛋白
fam125b 蛋白
fam125ba 蛋白
mvb12b 蛋白
RGD1309709 蛋白
zgc:152929 蛋白
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