MSH6 抗体
(MutS Homolog 6 (E. Coli) (MSH6))
This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq, Jul 2008].
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142 results
MSH6
适用: 人, 大鼠
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
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Latest Publications for our MSH6 抗体
: "Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer." in: Cold Spring Harbor molecular case studies, Vol. 3, Issue 5, (2017) (PubMed).: "DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication." in: Journal of virology, Vol. 85, Issue 23, pp. 12241-53, (2011) (PubMed).
: "Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90." in: The Journal of experimental medicine, Vol. 207, Issue 12, pp. 2751-65, (2010) (PubMed).
: "Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." in: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).
: "Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).
: "Germ-line mutations in mismatch repair genes associated with prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2460-7, (2009) (PubMed).
: "Mismatch Repair proteins are recruited to replicating DNA through interaction with Proliferating Cell Nuclear Antigen (PCNA)." in: Nucleic acids research, Vol. 36, Issue 1, pp. 67-75, (2008) (PubMed).
: "Hereditary cancer-associated missense mutations in hMSH6 uncouple ATP hydrolysis from DNA mismatch binding." in: The Journal of biological chemistry, Vol. 283, Issue 46, pp. 31641-8, (2008) (PubMed).
: "Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).
: "What the physician needs to know about Lynch syndrome: an update." in: Oncology (Williston Park, N.Y.), Vol. 19, Issue 4, pp. 455-63; discussion 463-4, 466, 469, (2005) (PubMed).
Aliases for MSH6 抗体
mutS homolog 6 (MSH6) 抗体mutS homolog 6 (E. coli) (msh6) 抗体
mutS homolog 6 (msh6) 抗体
mutS homolog 6 (Msh6) 抗体
DNA mismatch repair protein (msh6) 抗体
AU044881 抗体
AW550279 抗体
cb326 抗体
GTBP 抗体
GTMBP 抗体
Gtmbp 抗体
HNPCC5 抗体
HSAP 抗体
LOC100227810 抗体
p160 抗体
wu:fb36c12 抗体
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