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MSH6 抗体

MSH6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A10H7 unconjugated
产品编号 ABIN1724694
发货至: 中国
  • 抗原 See all MSH6 抗体
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MSH6 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of MSH6 expressed in E. coli.
    克隆位点
    3A10H7
    亚型
    IgG1
    Top Product
    Discover our top product MSH6 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Hess, Mendillo, Mazur, Kolodner: "Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).

    Lynch, Lynch: "What the physician needs to know about Lynch syndrome: an update." in: Oncology (Williston Park, N.Y.), Vol. 19, Issue 4, pp. 455-63; discussion 463-4, 466, 469, (2005) (PubMed).

  • 抗原
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    别名
    MSH6 (MSH6 产品)
    别名
    GTBP antibody, GTMBP antibody, HNPCC5 antibody, HSAP antibody, p160 antibody, cb326 antibody, wu:fb36c12 antibody, LOC100227810 antibody, AU044881 antibody, AW550279 antibody, Gtmbp antibody, mutS homolog 6 antibody, mutS homolog 6 (E. coli) antibody, DNA mismatch repair protein antibody, MSH6 antibody, msh6 antibody, Msh6 antibody
    背景

    Description: Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.

    Aliases: GTBP, HSAP, HNPCC5

    基因ID
    2956
    HGNC
    2956
    途径
    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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