MICA 产品
(MHC Class I Polypeptide-Related Sequence A (MICA))
Categories
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010].
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Featured MICA Categories
MICA 抗体
High quality antibodies with extensive validation data.
MICA ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MICA 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MICA 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IF, IHC (p)
Validations
- (2)
- (7)
Cat. No.
ABIN652566
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF (p)
Validations
- (1)
- (3)
Cat. No.
ABIN728788
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (f)
Validations
- (4)
Cat. No.
ABIN7504179
Quantity
100 μg
Datasheet
Datasheet
Recommended MICA ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968602
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN411398
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN577980
Quantity
96 tests
Datasheet
Datasheet
Recommended MICA 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275256
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275254
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275255
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MICA Products
: "Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells." in: The Journal of cell biology, Vol. 217, Issue 9, pp. 3267-3283, (2018) (PubMed).: "Scorpion venom activates natural killer cells in hepatocellular carcinoma via the NKG2D-MICA pathway." in: International immunopharmacology, Vol. 35, pp. 307-14, (2016) (PubMed).
: "Expression and Functional Role of α7 Nicotinic Receptor in Human Cytokine-stimulated Natural Killer (NK) Cells." in: The Journal of biological chemistry, Vol. 291, Issue 32, pp. 16541-52, (2016) (PubMed).
: "Genetically engineered mesenchymal stromal cells producing TNF? have tumour suppressing effect on human melanoma xenograft." in: The journal of gene medicine, (2015) (PubMed).
: "Allele Specific Expression of MICA Variants in Human Fibroblasts Suggests a Pathogenic Mechanism." in: The open rheumatology journal, Vol. 9, pp. 60-4, (2015) (PubMed).
: "A Thr72Ala polymorphism in the NKG2D gene is associated with early symptomatic congenital cytomegalovirus disease." in: Infection, Vol. 43, Issue 3, pp. 353-9, (2015) (PubMed).
: "Targeted activation of human V?9V?2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease." in: Cancer cell, Vol. 26, Issue 4, pp. 565-76, (2014) (PubMed).
: "An epithelial cell adhesion molecule- and CD3-bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro." in: Anticancer research, Vol. 34, Issue 8, pp. 4509-19, (2014) (PubMed).
: "NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors." in: Anticancer research, Vol. 34, Issue 8, pp. 4529-38, (2014) (PubMed).
: "Increase of IFN-γ and TNF-α production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor." in: Cancer cell international, Vol. 14, Issue 1, pp. 100, (2014) (PubMed).
Synonyms and alternative names related to MICA
MHC class I polypeptide-related sequence A (MICA), MIC-A, PERB11.1Protein level used designations for MICA
- HLA class I antigen
- MHC class I chain-related protein A
- stress inducible class I homolog
- F10 alpha chain-like
- class I histocompatibility antigen
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