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MIB1 产品

(Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))

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This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).

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Featured MIB1 Categories

MIB1 抗体

High quality antibodies with extensive validation data.

MIB1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MIB1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey
Application ELISA, WB, IHC, ICC, FACS
Validations
  • (5)
Cat. No. ABIN5542434
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7151063
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Rat
Application ELISA, WB, IHC (p)
Validations
  • (1)
  • (1)
Cat. No. ABIN2475692
Quantity 0.1 mg
Datasheet Datasheet

Recommended MIB1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1131155
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1131156
Quantity 96 tests
Datasheet Datasheet

Recommended MIB1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310903
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3093870
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3135970
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MIB1 Products

Scavuzzo, Chmielowiec, Yang, Wamble, Chaboub, Duraine, Tepe, Glasgow, Arenkiel, Brou, Deneen, Borowiak: "Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA." in: Cell reports, Vol. 25, Issue 13, pp. 3811-3827.e7, (2018) (PubMed).

Kwon, Dimitriadi, Terzic, Cable, Hart, Chitnis, Fischbeck, Burnett: "The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein." in: Molecular biology of the cell, Vol. 24, Issue 12, pp. 1863-71, (2013) (PubMed).

Jakobsen, Vanselow, Skogs, Toyoda, Lundberg, Poser, Falkenby, Bennetzen, Westendorf, Nigg, Uhlen, Hyman, Andersen: "Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods." in: The EMBO journal, Vol. 30, Issue 8, pp. 1520-35, (2011) (PubMed).

Bray: "Notch signalling: a simple pathway becomes complex." in: Nature reviews. Molecular cell biology, Vol. 7, Issue 9, pp. 678-89, (2006) (PubMed).

Itoh, Kim, Palardy, Oda, Jiang, Maust, Yeo, Lorick, Wright, Ariza-McNaughton, Weissman, Lewis, Chandrasekharappa, Chitnis: "Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta." in: Developmental cell, Vol. 4, Issue 1, pp. 67-82, (2003) (PubMed).

Jin, Blue, Dixon, Shao, Gallagher: "A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 46980-6, (2002) (PubMed).

Synonyms and alternative names related to MIB1

mindbomb E3 ubiquitin protein ligase 1 (MIB1), mindbomb E3 ubiquitin protein ligase 1 (Mib1), mindbomb E3 ubiquitin protein ligase 1 L homeolog (mib1.L), mindbomb E3 ubiquitin protein ligase 1 (mib1), mind bomb 1 (mib1), cg5841, CG5841, chunp6889, D-mib, D-mib1, DIP-1, dip-1, DIP1, Dmel\CG5841, Dmib, dmib1, E430019M12Rik, fe47f05, im:7148100, l(3)72CDa, l(3)72Db, LVNC7, MIB, Mib, mib, mib1, MIB1, Mib1, mib1/2, mind-bomb, mindbomb, mKIAA1323, wu:fe47f05, ZZANK2, ZZZ6

Protein level used designations for MIB1

  • DAPK-interacting protein 1
  • E3 ubiquitin-protein ligase MIB1
  • ubiquitin ligase mind bomb
  • zinc finger ZZ type with ankyrin repeat domain protein 2
  • DAPK-interacting protein-1
  • mind bomb homolog 1
  • mind bomb-1
  • skeletrophin
  • E3 ubiquitin-protein ligase mib1
  • mind bomb
  • mindbomb homolog 1
  • protein mind bomb
  • white tail
  • wit
  • CG5841 gene product from transcript CG5841-RA
  • CG5841-PA
  • CG5841-PB
  • Mind bomb homolog
  • Mindbomb1
  • RING-type E3 ubiquitin transferase mind-bomb
  • lethal (3) 72CDa
  • lethal (3) 72Db
  • mib1-PA
  • mib1-PB
  • mind bomb1
  • mind-bomb
  • mindbomb
  • mindbomb 1
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