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MEK2 抗体

(Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
MEK2 抗体  (AA 1-50) MEK2 抗体  (AA 1-50) MEK2 抗体 (AA 1-50) (ABIN726500)

MAP2K2 适用: 人, 小鼠 ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB 宿主: 兔 Polyclonal unconjugated

MEK2 抗体  (AA 262-292) MEK2 抗体  (AA 262-292) MEK2 抗体 (AA 262-292) (ABIN392485)

MAP2K2 适用: 人, 小鼠 IF, IHC (p), WB 宿主: 兔 Polyclonal RB3597 unconjugated

MEK2 抗体  (AA 200-229) MEK2 抗体  (AA 200-229) MEK2 抗体 (AA 200-229) (ABIN1881526)

MAP2K2 适用: 人 IHC (p), WB 宿主: 兔 Polyclonal RB12322 unconjugated

MEK2 抗体 by Grade

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MEK2 抗体 by 适用

Find MEK2 抗体 for a variety of species such as anti-Human MEK2, anti-Mouse MEK2, anti-Rat MEK2. The species listed below are among those available. Click on a link to go to the corresponding products.

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MEK2 抗体 by 抗原表位

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MEK2 抗体 by 克隆形成能力

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MEK2 抗体 by 克隆

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MEK2 抗体 by 标记

Find MEK2 抗体 with a specific conjugate such as Biotin, HRP, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MEK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (3)
  • (1)
Cat. No. ABIN726500
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF, IHC (p), WB
Validations
  • (5)
Cat. No. ABIN392485
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (5)
  • (4)
Cat. No. ABIN1881526
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, WB
Validations
  • (5)
  • (3)
Cat. No. ABIN1882178
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN7268640
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IP, WB
Validations
  • (4)
Cat. No. ABIN519254
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (4)
Cat. No. ABIN948323
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN7150701
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, IP, WB
Validations
  • (3)
Cat. No. ABIN6263216
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, IP, WB
Validations
  • (3)
Cat. No. ABIN6256556
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN7138844
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN6243254
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ICC, FACS, ELISA, WB
Validations
  • (3)
Cat. No. ABIN1724726
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IF, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN2855313
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Mouse
Application IF, WB
Validations
  • (3)
Cat. No. ABIN1499478
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MEK2 抗体

Guo, Wang, Li, Sun, Zhang, Hao: "Follicular fluid meiosis-activating sterol (FF-MAS) promotes meiotic resumption via the MAPK pathway in porcine oocytes." in: Theriogenology, (2019) (PubMed).

Shaul, Seger: "The MEK/ERK cascade: from signaling specificity to diverse functions." in: Biochimica et biophysica acta, Vol. 1773, Issue 8, pp. 1213-26, (2007) (PubMed).

Mittal, Peak-Chew, McMahon: "Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18574-9, (2006) (PubMed).

Burroughs, Oh, Barrett, DiAugustine et al.: "Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ..." in: Molecular cancer research : MCR, Vol. 1, Issue 4, pp. 312-22, (2003) (PubMed).

Tran, Maurer, Nagamine: "Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7177-88, (2003) (PubMed).

Li, Junttila, Han, Kähäri, Westermarck: "p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2." in: Cancer research, Vol. 63, Issue 13, pp. 3473-7, (2003) (PubMed).

Li, Inoki, Vacratsis, Guan: "The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 13663-71, (2003) (PubMed).

Aliases for MEK2 抗体

mitogen-activated protein kinase kinase 2 (MAP2K2) 抗体
mitogen-activated protein kinase kinase 2 (Map2k2) 抗体
mitogen activated protein kinase kinase 2 (Map2k2) 抗体
MAP kinase kinase 2 (MKK2) 抗体
mitogen-activated protein kinase kinase 2b (map2k2b) 抗体
AA589381 抗体
ATMKK2 抗体
CFC4 抗体
F27B13.50 抗体
F27B13_50 抗体
MAP KINASE KINASE 1 抗体
MAP kinase kinase 2 抗体
MAPKK2 抗体
MEK2 抗体
MK1 抗体
MK2 抗体
MKK2 抗体
PRKMK2 抗体
Prkmk2 抗体
zgc:172250 抗体
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