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MDM2 抗体

(Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues. [provided by RefSeq, Jul 2008].

Active filters:

  • 抗原: MDM2
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN802540
MDM2 抗体 (pThr218) (FITC) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 100 μL
发货至: 中国
ABIN802536
MDM2 抗体 (pThr218) (Cy3) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 100 μL
发货至: 中国
ABIN802537
MDM2 抗体 (pThr218) (Cy5) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 100 μL
发货至: 中国
ABIN874629
MDM2 抗体 (pSer186) (AbBy Fluor® 488) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN874631
MDM2 抗体 (pSer186) (AbBy Fluor® 555) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802535
MDM2 抗体 (pThr218) (Biotin) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802542
MDM2 抗体 (pThr218) (HRP) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802538
MDM2 抗体 (pThr218) (Cy5.5) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 100 μL
发货至: 中国
ABIN874628
MDM2 抗体 (pSer186) (AbBy Fluor® 350) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN7091376
MDM2 抗体 (AA 196-435) MDM2 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 G4W1
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN5006674
MDM2 抗体 (pSer186) (AbBy Fluor® 750) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802550
MDM2 抗体 (pSer186) (Biotin) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802555
MDM2 抗体 (pSer186) (FITC) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802557
MDM2 抗体 (pSer186) (HRP) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN2804083
MDM2 抗体 (pSer186) (AbBy Fluor® 594) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
  • 100 μL
发货至: 中国
ABIN874632
MDM2 抗体 (pSer186) (AbBy Fluor® 647) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802552
MDM2 抗体 (pSer186) (Cy5) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802553
MDM2 抗体 (pSer186) (Cy5.5) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN5006673
MDM2 抗体 (pSer186) (AbBy Fluor® 680) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN802554
MDM2 抗体 (pSer186) (Cy7) MDM2 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
FITC
抗体亚型
IgG
抗原表位
pThr218
产品编号 ABIN802540
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy3
抗体亚型
IgG
抗原表位
pThr218
产品编号 ABIN802536
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy5
抗体亚型
IgG
抗原表位
pThr218
产品编号 ABIN802537
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 488
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN874629
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 555
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN874631
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
抗体亚型
IgG
抗原表位
pThr218
产品编号 ABIN802535
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
HRP
抗体亚型
IgG
抗原表位
pThr218
产品编号 ABIN802542
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy5.5
抗体亚型
IgG
抗原表位
pThr218
产品编号 ABIN802538
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 350
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN874628
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
G4W1
标记
unconjugated
抗原表位
AA 196-435
产品编号 ABIN7091376
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 750
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN5006674
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN802550
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
FITC
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN802555
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
HRP
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN802557
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 594
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN2804083
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 647
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN874632
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy5
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN802552
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy5.5
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN802553
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 680
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN5006673
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy7
抗体亚型
IgG
抗原表位
pSer186
产品编号 ABIN802554

Latest Publications for our MDM2 抗体

Duan, Ma, Huang, DAmore, Zhang, Lei et al.: "The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and Proliferation and ..." in: The Journal of biological chemistry, Vol. 291, Issue 31, pp. 16339-47, (2017) (PubMed).

Fragou, Tzimagiorgis, Karageorgopoulos, Barbetakis, Lazopoulos, Papaioannou, Haitoglou, Kouidou: "Increased Δ133p53 mRNA in lung carcinoma corresponds with reduction of p21 expression." in: Molecular medicine reports, Vol. 15, Issue 4, pp. 1455-1460, (2017) (PubMed).

Zhou, Duan, Ma, Wu, Hu, Chen, Chee, Cui, Samad, Matsubara, Mukai, DAmore, Lei: "Introduction of the MDM2 T309G Mutation in Primary Human Retinal Epithelial Cells Enhances Experimental Proliferative Vitreoretinopathy." in: Investigative ophthalmology & visual science, Vol. 58, Issue 12, pp. 5361-5367, (2017) (PubMed).

Mokhtarzadeh, Parhiz, Hashemi, Abnous, Ramezani: "P53-Derived peptides conjugation to PEI: an approach to producing versatile and highly efficient targeted gene delivery carriers into cancer cells." in: Expert opinion on drug delivery, Vol. 13, Issue 4, pp. 477-91, (2016) (PubMed).

Guo, Yang, Yang, Linghu, Zhan, Brock, Herman, Zhang, Guo: "RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel." in: Oncotarget, Vol. 6, Issue 6, pp. 4202-13, (2015) (PubMed).

Xiao, Zhou, Yi, Luo, Jiang, Tian, Li, Xue: "Fra-1 is downregulated in cervical cancer tissues and promotes cervical cancer cell apoptosis by p53 signaling pathway in vitro." in: International journal of oncology, Vol. 46, Issue 4, pp. 1677-84, (2015) (PubMed).

Li, Liu, Wang, Fang, Shen, Cai, Gao, Li, Zhang, Ye: "The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer." in: The Journal of biological chemistry, Vol. 290, Issue 37, pp. 22649-61, (2015) (PubMed).

Liao, Xiao, Zhu, Zheng, He, Pei, Li, Zhou: "CD38 is highly expressed and affects the PI3K/Akt signaling pathway in cervical cancer." in: Oncology reports, Vol. 32, Issue 6, pp. 2703-9, (2014) (PubMed).

Khoronenkova, Dianova, Parsons, Dianov: "USP7/HAUSP stimulates repair of oxidative DNA lesions." in: Nucleic acids research, Vol. 39, Issue 7, pp. 2604-9, (2011) (PubMed).

Lei, Velez, Kazlauskas: "Pathological signaling via platelet-derived growth factor receptor {alpha} involves chronic activation of Akt and suppression of p53." in: Molecular and cellular biology, Vol. 31, Issue 9, pp. 1788-99, (2011) (PubMed).

Aliases for MDM2 抗体

MDM2 proto-oncogene (MDM2) 抗体
MDM2 proto-oncogene S homeolog (mdm2.S) 抗体
MDM2 proto-oncogene (Mdm2) 抗体
Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) (MDM2) 抗体
MDM2 oncogene, E3 ubiquitin protein ligase (mdm2) 抗体
transformed mouse 3T3 cell double minute 2 (Mdm2) 抗体
1700007J15Rik 抗体
AA415488 抗体
ACTFS 抗体
hdm2 抗体
HDMX 抗体
Mdm-2 抗体
zgc:109834 抗体
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