Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity.
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Xu, Zheng, Zhang, Zhao, Zhang, Wu, Wu, Wang, Wang, Zhang: "MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 13, Issue 7, pp. 3233-8, (2012) (PubMed).
Aliases for MCRS1 抗体
Reduction in Cnn dots 5 (Rcd5) 抗体 microspherule protein 1 L homeolog (mcrs1.L) 抗体 microspherule protein 1 (mcrs1) 抗体 microspherule protein 1 (MCRS1) 抗体 microspherule protein 1 (CpipJ_CPIJ004521) 抗体 microspherule protein 1 (Tsp_07041) 抗体 microspherule protein 1 (Tsp_07058) 抗体 microspherule protein 1 (Tsp_06917) 抗体 microspherule protein 1 (Mcrs1) 抗体 C78274 抗体 CG1135 抗体 dMCRS1 抗体 dMCRS2 抗体 Dmel\\CG1135 抗体 ICP22BP 抗体 INO80Q 抗体 l(3)r0166 抗体 l(3)rG166 抗体 MCRS1 抗体 MCRS2 抗体 mcrs2 抗体 msp58 抗体 MSP58 抗体 p78 抗体 P78 抗体 wu:fj97a11 抗体 zgc:66428 抗体 zgc:77376 抗体