MCM10 抗体
(Minichromosome Maintenance Deficient 10 (MCM10))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| MCM10 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MCM10 抗体 (AA 616-875) | 人 | 兔 Polyclonal |
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| MCM10 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MCM10 抗体 (AA 1-874) | 人 | 小鼠 Polyclonal |
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| MCM10 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| MCM10 抗体 (AA 40-89) | 人, 小鼠, 大鼠, 犬, 猴, Bat | 兔 Polyclonal |
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| MCM10 抗体 (AA 648-697) | 人, 犬, Cow, 兔, 猴 | 兔 Polyclonal |
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| MCM10 抗体 (N-Term) | 人, 小鼠 | 兔 Polyclonal |
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| MCM10 抗体 (AA 600-650) | 人 | 兔 Polyclonal |
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| MCM10 抗体 (AA 1-874) | 人 | 兔 Polyclonal |
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| MCM10 抗体 (AA 600-650) | 人, 猴 | 兔 Polyclonal |
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| MCM10 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MCM10 抗体 (AA 1-874) | 人 | 兔 Polyclonal |
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| MCM10 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| MCM10 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| MCM10 抗体 (Middle Region) | 人, 犬, Cow, 兔, 马, Pig | 兔 Polyclonal |
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| MCM10 抗体 (N-Term) | 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠 | 兔 Polyclonal |
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| MCM10 抗体 (AA 616-875) | 人 | 兔 Polyclonal |
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| MCM10 抗体 (Alexa Fluor 680) | 人 | 兔 Polyclonal |
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| MCM10 抗体 (Alexa Fluor 555) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 616-875
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-874
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 600-650
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-874
Primary Antibody
- WB (Western Blotting: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 600-650
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-874
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 犬, Cow, 兔, 马, Pig
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 616-875
Latest Publications for our MCM10 抗体
: "Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication." in: PLoS ONE, Vol. 10, Issue 10, pp. e0140645, (2015) (PubMed).
: "Efficient expression and purification of human replication fork-stabilizing factor, Claspin, from mammalian cells: DNA-binding activity and novel protein interactions." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 16, Issue 8, pp. 842-56, (2011) (PubMed).
: "Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication." in: Molecular biology of the cell, Vol. 18, Issue 10, pp. 4085-95, (2007) (PubMed).
: "The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30631-44, (2006) (PubMed).
: "Efficient expression and purification of human replication fork-stabilizing factor, Claspin, from mammalian cells: DNA-binding activity and novel protein interactions." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 16, Issue 8, pp. 842-56, (2011) (PubMed).
: "Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication." in: Molecular biology of the cell, Vol. 18, Issue 10, pp. 4085-95, (2007) (PubMed).
: "The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30631-44, (2006) (PubMed).
Aliases for MCM10 抗体
Minichromosome maintenance 10 (Mcm10) 抗体minichromosome maintenance 10 replication initiation factor (MCM10) 抗体
minichromosome maintenance 10 replication initiation factor (Mcm10) 抗体
minichromosome maintenance 10 replication initiation factor L homeolog (mcm10.L) 抗体
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AU018508 抗体
C79164 抗体
C330019M07Rik 抗体
CG9241 抗体
CNA43 抗体
Dmel\\CG9241 抗体
DmMCM10 抗体
DNA43 抗体
mcm10 抗体
Scim19 抗体
xmcm10 抗体
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