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MCM10 抗体

MCM10 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7245593
发货至: 中国
  • 抗原 See all MCM10 抗体
    MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
    适用
    • 24
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 23
    • 1
    克隆类型
    • 24
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM10 antibody is un-conjugated
    应用范围
    • 15
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human MCM10
    亚型
    IgG
    Top Product
    Discover our top product MCM10 Primary Antibody
  • 应用备注
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
    别名
    MCM10 (MCM10 产品)
    别名
    CG9241 antibody, DmMCM10 antibody, Dmel\\CG9241 antibody, Scim19 antibody, mcm10 antibody, CNA43 antibody, DNA43 antibody, xmcm10 antibody, 2410041F14Rik antibody, AU018508 antibody, C330019M07Rik antibody, C79164 antibody, Minichromosome maintenance 10 antibody, minichromosome maintenance 10 replication initiation factor antibody, minichromosome maintenance 10 replication initiation factor L homeolog antibody, Mcm10 antibody, MCM10 antibody, mcm10.L antibody
    背景
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
    UniProt
    Q7L590
    途径
    Mitotic G1-G1/S Phases, DNA Replication
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