MAPKAP Kinase 5 蛋白
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012].
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13 results
custom-made
MAPKAPK5
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
MAPKAPK5
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
Active
MAPKAPK5
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
NC, S
Inactive
custom-made
MAPKAPK5
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
MAPKAPK5
宿主: 人
宿主: Insect cells (Sf9)
Recombinant
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Active
MAPKAPK5
宿主: 人
宿主: Insect Cells
Recombinant
70 % - 90 %
Func
Active
Aliases for MAPKAP Kinase 5 蛋白
mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5) 蛋白mitogen-activated protein kinase-activated protein kinase 5 (mapkapk5) 蛋白
MAP kinase-activated protein kinase 5 (Mapkapk5) 蛋白
mitogen-activated protein kinase-activated protein kinase 5 (Mapkapk5) 蛋白
MAPKAP-K5 蛋白
MAPKAPK5 蛋白
MK-5 蛋白
MK5 蛋白
PRAK 蛋白
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