MARK1 蛋白
(MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) (By similarity).
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5 results
custom-made
MARK1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
MARK1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Aliases for MARK1 蛋白
MAP/microtubule affinity-regulating kinase 1 S homeolog (mark1.S) 蛋白microtubule affinity regulating kinase 1 (MARK1) 蛋白
MAP/microtubule affinity-regulating kinase 1 (mark1) 蛋白
microtubule affinity regulating kinase 1 (mark1) 蛋白
MAP/microtubule affinity regulating kinase 1 (Mark1) 蛋白
microtubule affinity regulating kinase 1 (Mark1) 蛋白
AW491150 蛋白
B930025N23Rik 蛋白
Emk3 蛋白
MARK 蛋白
MARK1 蛋白
MGC80341 蛋白
mKIAA1477 蛋白
mPar-1c 蛋白
Par-1c 蛋白
Par1c 蛋白
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