LIN28B 抗体
(Lin-28 Homolog B (LIN28B))
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012].
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Latest Publications for our LIN28B 抗体
: "Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma." in: Blood, Vol. 120, Issue 5, pp. 1048-59, (2012) (PubMed).: "Role of ribosomal protein RPS2 in controlling let-7a expression in human prostate cancer." in: Molecular cancer research : MCR, Vol. 9, Issue 1, pp. 36-50, (2011) (PubMed).
: "IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2." in: Cancer research, Vol. 71, Issue 6, pp. 2172-82, (2011) (PubMed).
: "Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma." in: Gene, Vol. 384, pp. 51-61, (2006) (PubMed).
Aliases for LIN28B 抗体
lin-28 homolog B (LIN28B) 抗体lin-28 homolog B (lin28b) 抗体
lin-28 homolog B S homeolog (lin28b.S) 抗体
lin-28 homolog B (C. elegans) (Lin28b) 抗体
lin-28 homolog B (C. elegans) (LIN28B) 抗体
lin-28 homolog B (Lin28b) 抗体
2810403D23Rik 抗体
csdd2 抗体
CSDD2 抗体
D030047M17Rik 抗体
LIN-28 抗体
Lin-28.2 抗体
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