LILRB1 抗体
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our LILRB1 抗体
: "Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells." in: International journal of nanomedicine, Vol. 13, pp. 6941-6960, (2018) (PubMed).: "Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells." in: Neoplasia (New York, N.Y.), Vol. 13, Issue 9, pp. 822-30, (2011) (PubMed).
: "Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 7, pp. 3966-76, (2011) (PubMed).
: "Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 12, pp. 6701-9, (2011) (PubMed).
: "The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 7, pp. 4509-20, (2009) (PubMed).
: "Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals." in: The Journal of experimental medicine, Vol. 205, Issue 8, pp. 1797-805, (2008) (PubMed).
: "HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition." in: International immunology, Vol. 13, Issue 2, pp. 193-201, (2001) (PubMed).
: "Identification of the CD85 antigen as ILT2, an inhibitory MHC class I receptor of the immunoglobulin superfamily." in: Journal of leukocyte biology, Vol. 65, Issue 6, pp. 841-5, (1999) (PubMed).
: "A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells." in: Journal of leukocyte biology, Vol. 66, Issue 3, pp. 375-81, (1999) (PubMed).
: "A 72-kD B cell-associated surface glycoprotein expressed at high levels in hairy cell leukaemia and plasma cell neoplasms." in: Clinical and experimental immunology, Vol. 85, Issue 3, pp. 429-35, (1991) (PubMed).
Aliases for LILRB1 抗体
leukocyte immunoglobulin like receptor B1 (LILRB1) 抗体CD85J 抗体
ILT-2 抗体
ILT2 抗体
LIR-1 抗体
LIR1 抗体
MIR-7 抗体
MIR7 抗体
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