LAT 抗体
(Linker For Activation of T Cells (LAT))
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Recombinant LAT 抗体 (pTyr220) (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (pTyr220) (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (pTyr220) (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (pTyr220) (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (pTyr220) (Biotin) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| LAT 抗体 (pTyr255) (Biotin) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| LAT 抗体 (pTyr255) (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| LAT 抗体 (pTyr255) (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| LAT 抗体 (pTyr255) (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| LAT 抗体 (pTyr255) (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| LAT 抗体 (Center) | 人 | 兔 Polyclonal |
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| Recombinant LAT 抗体 (Alexa Fluor 750) | 人 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (Alexa Fluor 488) | 人 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (Alexa Fluor 405) | 人 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (Alexa Fluor 594) | 人 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (Alexa Fluor 680) | 人 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (Alexa Fluor 555) | 人 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (Alexa Fluor 647) | 人 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (Alexa Fluor 350) | 人 | 兔 Monoclonal |
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| Recombinant LAT 抗体 (Biotin) | 人 | 兔 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- SR1644
- 标记
- Alexa Fluor 594
- 蛋白类型
- Recombinant Antibody
- 抗原表位
- pTyr220
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- SR1644
- 标记
- Alexa Fluor 647
- 蛋白类型
- Recombinant Antibody
- 抗原表位
- pTyr220
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- SR1644
- 标记
- Alexa Fluor 680
- 蛋白类型
- Recombinant Antibody
- 抗原表位
- pTyr220
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- SR1644
- 标记
- Alexa Fluor 750
- 蛋白类型
- Recombinant Antibody
- 抗原表位
- pTyr220
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- SR1644
- 标记
- Biotin
- 蛋白类型
- Recombinant Antibody
- 抗原表位
- pTyr220
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗原表位
- pTyr255
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 750
- 抗原表位
- pTyr255
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 647
- 抗原表位
- pTyr255
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 488
- 抗原表位
- pTyr255
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 594
- 抗原表位
- pTyr255
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 750
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 488
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 405
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 594
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 680
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 555
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 647
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 350
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Biotin
- 蛋白类型
- Recombinant Antibody
Latest Publications for our LAT 抗体
: "Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation." in: The Journal of experimental medicine, Vol. 215, Issue 4, pp. 1245-1265, (2019) (PubMed).
: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival." in: Molecular and cellular biology, Vol. 27, Issue 12, pp. 4406-15, (2007) (PubMed).
: "Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells." in: Journal of immunological methods, Vol. 328, Issue 1-2, pp. 139-51, (2007) (PubMed).
: "Topography of plasma membrane microdomains and its consequences for mast cell signaling." in: European journal of immunology, Vol. 36, Issue 10, pp. 2795-806, (2006) (PubMed).
: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, (2005) (PubMed).
: "Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads." in: The EMBO journal, Vol. 23, Issue 7, pp. 1441-51, (2004) (PubMed).
: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." in: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, (2004) (PubMed).
: "Right time, right place: the organization of membrane proximal signaling." in: Seminars in immunology, Vol. 17, Issue 1, pp. 35-49, (2004) (PubMed).
: "Adaptor proteins in lymphocyte activation." in: Current opinion in immunology, Vol. 15, Issue 3, pp. 269-76, (2003) (PubMed).
: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival." in: Molecular and cellular biology, Vol. 27, Issue 12, pp. 4406-15, (2007) (PubMed).
: "Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells." in: Journal of immunological methods, Vol. 328, Issue 1-2, pp. 139-51, (2007) (PubMed).
: "Topography of plasma membrane microdomains and its consequences for mast cell signaling." in: European journal of immunology, Vol. 36, Issue 10, pp. 2795-806, (2006) (PubMed).
: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, (2005) (PubMed).
: "Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads." in: The EMBO journal, Vol. 23, Issue 7, pp. 1441-51, (2004) (PubMed).
: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." in: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, (2004) (PubMed).
: "Right time, right place: the organization of membrane proximal signaling." in: Seminars in immunology, Vol. 17, Issue 1, pp. 35-49, (2004) (PubMed).
: "Adaptor proteins in lymphocyte activation." in: Current opinion in immunology, Vol. 15, Issue 3, pp. 269-76, (2003) (PubMed).
Aliases for LAT 抗体
linker for activation of T-cells (LAT) 抗体linker for activation of T cells (lat) 抗体
linker for activation of T cells (Lat) 抗体
LAT 抗体
lat 抗体
LAT1 抗体
pp36 抗体
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