KSR2 抗体
(Kinase Suppressor of Ras 2 (KSR2))
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
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Latest Publications for our KSR2 抗体
: "Kinase suppressor of Ras 2 (KSR2) regulates tumor cell transformation via AMPK." in: Molecular and cellular biology, Vol. 32, Issue 18, pp. 3718-31, (2012) (PubMed).: "Kinase suppressor of Ras 2 is involved in regulation of cell proliferation and is up-regulated in human invasive ductal carcinomas of breast." in: Experimental oncology, Vol. 32, Issue 3, pp. 209-12, (2011) (PubMed).
: "1,25-dihydroxyvitamin D3 enhances the apoptotic activity of MDM2 antagonist nutlin-3a in acute myeloid leukemia cells expressing wild-type p53." in: Molecular cancer therapeutics, Vol. 9, Issue 5, pp. 1158-68, (2010) (PubMed).
: "KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity." in: Cell metabolism, Vol. 10, Issue 5, pp. 366-78, (2009) (PubMed).
Aliases for KSR2 抗体
kinase suppressor of ras 2 (KSR2) 抗体kinase suppressor of ras 2 (Ksr2) 抗体
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