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KSR2 抗体 (Internal Region)

KSR2 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257612
发货至: 中国
  • 抗原 See all KSR2 抗体
    KSR2 (Kinase Suppressor of Ras 2 (KSR2))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 小鼠
    宿主
    • 39
    • 6
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 19
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KSR2 antibody is un-conjugated
    应用范围
    • 33
    • 29
    • 15
    • 13
    • 7
    • 6
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    KSR2 Antibody detects endogenous levels of total KSR2.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human KSR2, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product KSR2 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    KSR2 (Kinase Suppressor of Ras 2 (KSR2))
    别名
    KSR2 (KSR2 产品)
    别名
    kinase suppressor of ras 2 antibody, KSR2 antibody, Ksr2 antibody
    背景

    Description: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

    Gene: KSR2

    分子量
    108 kDa
    基因ID
    283455
    UniProt
    Q6VAB6
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