电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

KSR2 抗体 (AA 671-720)

The 兔 多克隆 anti-KSR2 antibody (ABIN1533965) specifically detects KSR2 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1533965
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KSR2 抗体 (AA 671-720) (ABIN1533965)

抗原

See all KSR2 抗体
KSR2 (Kinase Suppressor of Ras 2 (KSR2))

适用

  • 45
  • 16
  • 1
人, 小鼠

宿主

  • 38
  • 7
兔

克隆类型

  • 41
  • 4
多克隆

标记

  • 23
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KSR2 antibody is un-conjugated

应用范围

  • 31
  • 23
  • 15
  • 10
  • 9
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 671-720

    原理

    Ksr2 Antibody

    特异性

    Ksr2 Polyclonal Antibody detects endogenous levels of Ksr2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human KSR2. AA range:671-720

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    KSR2 (Kinase Suppressor of Ras 2 (KSR2))

    别名

    KSR2

    背景

    Synonyms: KSR2, Kinase suppressor of Ras 2, hKSR2

    Background: domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.,PTM:Phosphorylated on Ser-474 by MARK3.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF.,tissue specificity:Mainly expressed in brain and kidney.,

    Gene Name: KSR2

    Protein Name: Kinase suppressor of Ras 2

    分子量

    107 kDa

    基因ID

    283455

    OMIM

    610737

    UniProt

    Q6VAB6
You are here: