KPNA1 抗体
(Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].
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Latest Publications for our KPNA1 抗体
: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).
: "Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box." in: Biochemical and biophysical research communications, Vol. 462, Issue 3, pp. 201-7, (2015) (PubMed).
: "Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery." in: The FEBS journal, Vol. 278, Issue 9, pp. 1561-72, (2011) (PubMed).
: "Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration." in: Brain : a journal of neurology, Vol. 133, Issue Pt 6, pp. 1763-71, (2010) (PubMed).
: "Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2." in: The Journal of biological chemistry, Vol. 283, Issue 14, pp. 8984-94, (2008) (PubMed).
: "Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport." in: Traffic (Copenhagen, Denmark), Vol. 8, Issue 9, pp. 1164-78, (2007) (PubMed).
: "RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 16, pp. 7633-7, (1994) (PubMed).
: "Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box." in: Biochemical and biophysical research communications, Vol. 462, Issue 3, pp. 201-7, (2015) (PubMed).
: "Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery." in: The FEBS journal, Vol. 278, Issue 9, pp. 1561-72, (2011) (PubMed).
: "Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration." in: Brain : a journal of neurology, Vol. 133, Issue Pt 6, pp. 1763-71, (2010) (PubMed).
: "Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2." in: The Journal of biological chemistry, Vol. 283, Issue 14, pp. 8984-94, (2008) (PubMed).
: "Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport." in: Traffic (Copenhagen, Denmark), Vol. 8, Issue 9, pp. 1164-78, (2007) (PubMed).
: "RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 16, pp. 7633-7, (1994) (PubMed).
Aliases for KPNA1 抗体
karyopherin subunit alpha 1 (KPNA1) 抗体karyopherin subunit alpha 1 (Kpna1) 抗体
importin alpha-1 subunit (EHI_124900) 抗体
karyopherin (importin) alpha 1 (Kpna1) 抗体
karyopherin alpha 1 (importin alpha 5) (kpna1) 抗体
AW494490 抗体
IPOA5 抗体
mSRP1 抗体
NPI-1 抗体
NPI1 抗体
RCH2 抗体
Rch2 抗体
si:ch211-161h7.7 抗体
SRP1 抗体
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