Kallikrein 6 ELISA 试剂盒
Quick Overview for Kallikrein 6 ELISA 试剂盒 (ABIN6719698)
抗原
See all Kallikrein 6 (KLK6) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 78 pg/mL
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Supplier Product No.
- koa0488
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Supplier
- Rockland
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原理
- Human Kallikrein-6 Sandwich ELISA Kit for Quantitative Detection
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品牌
- AccuSignal™
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Analytical Method
- Quantitative
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特异性
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Production: Natural and recombinant human Kallikrein-6. There is no detectable cross-reactivity with other relevant proteins.
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灵敏度
- < 3 pg/mL
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组件
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- Antibody-coated 96-well plate
- Target Protein Standard
- Detection antibody
- Detection reagent
- Diluent buffers
- Wash buffers
- Substrate Solution
- Stop solutions
- Adhesive covers
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Kallikrein 6 (KLK6) ELISA Kit
KLK6 适用: 人 Colorimetric Competition ELISA 1.52 pg/mL - 123.5 pg/mL Cerebrospinal Fluid, Milk, Plasma, Serum, Tissue Homogenate
Kallikrein 6 (KLK6) ELISA KitKLK6 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cerebrospinal Fluid, Milk, Plasma, Serum, Tissue Homogenate
Kallikrein 6 (KLK6) ELISA KitKLK6 适用: 小鼠 Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cerebrospinal Fluid, Milk, Plasma, Serum
Kallikrein 6 (KLK6) ELISA KitKLK6 适用: 大鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Kallikrein 6 (KLK6) ELISA KitKLK6 适用: 人 AA 22-244 Colorimetric Sandwich ELISA 78-5000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma (EDTA), Plasma (heparin), Serum, Tissue Homogenate
Kallikrein 6 (KLK6) ELISA KitKLK6 适用: 人 Colorimetric Sandwich ELISA 0.6-150 ng/mL Cell Culture Supernatant, Plasma, Serum
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应用备注
- Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL, 78pg/mL human Kallikrein-6 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, cell lysates, serum, plasma(heparin, EDTA) or tissue homogenates to each empty well. We recommend that each human Kallikrein-6 standard solution and each sample is measured in duplicate.
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说明
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Standard: Expression system for standard: NSO, Immunogen sequence: L22-K244
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样本量
- 100 μL
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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有效期
- 12 months
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- Kallikrein 6 (KLK6)
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别名
- Kallikrein-6
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背景
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Synonyms: Kallikrein-6, Klk6, KLK6_HUMAN, Neurosin, Protease M, Serine protease 18, Serine protease 9, SP59, Zyme
Background: KLK6(Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.
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基因ID
- 5653
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NCBI登录号
- NP_001012982
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UniProt
- Q92876
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途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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