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TEK ELISA 试剂盒

The 人 TEK ELISA Kit (ABIN2042679) is a Colorimetric ELISA Kit designed to quantify 人 TEK.
产品编号 ABIN2042679
发货至: 中国
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Quick Overview for TEK ELISA 试剂盒 (ABIN2042679)

抗原

See all TEK ELISA试剂盒
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

6-10000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    6 pg/mL

    交叉反应 (详细)

    There is cross-reactivates with human TIE1< 0.1 % .

    灵敏度

    < 5 pg/mL

    组件

    96-well plate pre-coated with anti-TIE2, Human
    Lyophilized recombinant TIE2, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human TIE2 in cell culture supernates, serum and plasma (heparin, EDTA).Tyrosine kinase with Ig and EGF homology domain 2 (Tie-2), also called TEK tyrosine kinase, endothelial (TEK). Tie-2 and tie-1 are expressed in early embryonic vascular system and in maternal decidual vascular endothelial cells, where the vasculature undergoes an active angiogenesis. Tie-2, but not tie-1, expression was also detected in extraembryonic mesoderm of the amnion. Angiogenesis is coordinated with follicular cell growth in goitrogenesis. The angiopoietins, Ang-1 and Ang-2, are angiogenic growth factors acting through Tie-2. Tie-2 and Ang-1 are expressed in thyroid epithelial and endothelial cells, and Tie-2 is regulated by TSH and cAMP in follicular cells. And Tie-2 expression is increased in goiter in both humans and rats, consistent with a role in goitrogenesis. Tie2/Ang-1 signaling pathway plays a critical role in the maintenance of HSCs in a quiescent state in the BM niche. And the Tie-2 signaling pathway is also critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all TEK ELISA试剂盒

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    别名

    TIE2

    基因ID

    7010

    UniProt

    Q02763

    途径

    RTK signaling, Growth Factor Binding
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