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MME ELISA 试剂盒

This 小鼠 MME ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 MME.
产品编号 ABIN2042615
发货至: 中国

Quick Overview for MME ELISA 试剂盒 (ABIN2042615)

抗原

See all MME ELISA试剂盒
MME (Membrane Metallo-Endopeptidase (MME))

适用

  • 6
  • 6
  • 2
  • 1
小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

93.7-6000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    93.7 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 10 pg/mL

    组件

    96-well plate pre-coated with anti-Neprilysin/CD10, Mouse
    Lyophilized recombinant Neprilysin/CD10, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Mouse Neprilysin/CD10 in cell culture supernates, serum and plasma (heparin, EDTA).Neprilysin, also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), CD10, and common acute lymphoblastic leukemia antigen (CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably theamyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease, this gene is localized to human chromosome 3 by study of somatic cell hybrids and regionalized the location to 3q21-q27 by in situ hybridization. By cDNA transfection analysis, Neprilysin is confirmed as a functional neutral endopeptidase of the type that has previously been called enkephalinase. Neprilysin has also been called atriopeptidase. Atriopeptidase specifically degrades atrial natriuretic factor. A specific enzyme inhibitor was developed and reported that it had effects similar to those of low-dose ANF infusion. These effects include diuresis, natriuresis, vasodilatation, and suppression of the renin-angiotensin-aldosterone system.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all MME ELISA试剂盒

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    Neprilysin/CD10

    物质类

    Chemical

    基因ID

    17380

    UniProt

    Q61391

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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