电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SensoLyte® 520 Neprilysin Activity Assay Kit

Act, FRET Fluorometric
产品编号 ABIN1882538
发货至: 中国
  • 抗原 See all MME 试剂盒
    MME (Membrane Metallo-Endopeptidase (MME))
    检测方法
    Fluorometric
    应用范围
    Activation (Act), Fluorescence Resonance Energy Transfer Microscopy (FRET)
    品牌
    SensoLyte®
    产品特性
    The SensoLyte® 520 Neprilysin Assay Kit employs a novel internally quenched 5-FAM/QXL™ FRET substrate for the detection of neprilysin activity. The enzyme cleaves the FRET substrate into two separate fragments resulting in the release of 5-FAM fluorescence, which can be monitored at excitation /emission= 490/520 nm. The long wavelength fluorescence of 5-FAM is less interfered by the autofluorescence of components in biological samples and test compounds. The assay can detect as low as 0.78 ng/mL of active neprilysin.
    Top Product
    Discover our top product MME ELISA Kit
  • 说明

    FRET-based Assay Kit

    限制
    仅限研究用
  • 注意事项
    Protect Components A abd B from light and moisture.
    储存条件
    -80 °C
    储存方法
    Store all kit Components at -20 °C, except Component C, which should be stored at -80 °C.
  • 抗原
    MME (Membrane Metallo-Endopeptidase (MME))
    别名
    Neprilysin (MME 产品)
    别名
    CALLA Kit, CD10 Kit, NEP Kit, SFE Kit, 6030454K05Rik Kit, C85356 Kit, Nep Kit, neprilysin Kit, membrane metalloendopeptidase Kit, membrane metallo endopeptidase Kit, membrane metallo-endopeptidase Kit, MME Kit, Mme Kit
    物质类
    Chemical
    背景
    Neprilysin (NEP) is a transmembrane metallopeptidase normally expressed by a variety of tissues. It is also known as neutral endopeptidase, and enkephalinase. NEP cleaves peptides at the N-terminal side of hydrophobic amino acid residues and is responsible for the degradation and inactivation of a variety of physiological substrates. NEP is a major extracellular amyloid beta-peptide degrading enzyme in the brain and targeting NEP is considered a potential therapeutic strategy for the prevention and treatment of Alzheimer's disease. NEP has also been implicated in the pathogenesis of hypertension, diabetes, and cancer.
You are here:
客服