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MERTK ELISA 试剂盒

This 小鼠 MERTK ELISA Kit specifically detects MERTK .
产品编号 ABIN2042591
发货至: 中国
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Quick Overview for MERTK ELISA 试剂盒 (ABIN2042591)

抗原

See all MERTK ELISA试剂盒
MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

适用

  • 7
  • 3
  • 1
小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

8-5000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    8 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 10 pg/mL

    组件

    96-well plate pre-coated with anti-MER/MERTK, Mouse
    Lyophilized recombinant MER/MERTK, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Mouse MER/MERTK in cell culture supernates, cell lysates, tissue homogenates and serum.Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. This gene also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all MERTK ELISA试剂盒

    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

    别名

    MER/MERTK

    基因ID

    17289

    UniProt

    Q60805

    途径

    RTK signaling
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