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ErbB2/Her2 ELISA 试剂盒

This 人 ErbB2/Her2 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 ErbB2/Her2.
产品编号 ABIN2042457
发货至: 中国

Quick Overview for ErbB2/Her2 ELISA 试剂盒 (ABIN2042457)

抗原

See all ErbB2/Her2 ELISA试剂盒
ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

适用

  • 14
  • 8
  • 7
  • 1

检测方法

Colorimetric

实验类型

Competition ELISA

检测范围

15.6-1000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    15.6 pg/mL

    品牌

    BioAssay™

    Analytical Method

    Quantitative

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 10 pg/mL

    组件

    96-well plate pre-coated with anti-ErbB-2, Human
    Lyophilized recombinant ErbB-2, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human ErbB-2 in cell culture supernates, serum, plasma (heparin, EDTA) and tissue homogenates.HER2/neu (also known as ErbB-2) stands for "Human Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2/neu has also been designated as CD340 (cluster of differentiation 340) and p185. It is encoded by the ERBB2 gene.HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. It is encoded within the genome by HER2/neu, a known proto-oncogene. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. However, ErbB receptors dimerise on ligand binding, and HER2 is the preferential dimerisation partner of other members of the ErbB family.1 The HER2 gene is a proto-oncogene located at the long arm of human chromosome 17(17q21-q22)2.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all ErbB2/Her2 ELISA试剂盒

    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

    别名

    ErbB-2

    基因ID

    2064

    UniProt

    P04626

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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