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KDM4C 抗体

(Lysine (K)-Specific Demethylase 4C (KDM4C))
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Active filters:

  • 抗原: KDM4C
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN2442475
KDM4C 抗体 (N-Term) KDM4C · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN7840212
KDM4C 抗体 KDM4C · Primary Antibody 人, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 200 μL
发货至: 中国
ABIN2750372
KDM4C 抗体 (AA 490-530) (FITC) KDM4C · Primary Antibody 人, 猴 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • 100 μg
发货至: 中国
ABIN8122716
KDM4C 抗体 (AA 737-787) KDM4C · Primary Antibody 人, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • 50 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗原表位
N-Term
产品编号 ABIN2442475
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
产品编号 ABIN7840212
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
适用
人, 猴
宿主
兔
克隆形成能力
Polyclonal
标记
FITC
抗体亚型
IgG
抗原表位
AA 490-530
产品编号 ABIN2750372
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 737-787
产品编号 ABIN8122716

Latest Publications for our KDM4C 抗体

Kalainayakan, Ghosh, Dey, Fitzgerald, Sohoni, Konduri, Garrossian, Liu, Zhang: "Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression." in: Scientific reports, Vol. 9, Issue 1, pp. 1405, (2019) (PubMed).

Wu, Cheng, Yeh, Li, Chen, Sit, Chuu, Kung, Chien, Wang: "KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis." in: Cell death & disease, Vol. 10, Issue 2, pp. 68, (2019) (PubMed).

Xu, Moresco, Chang, Mukim, Smith, Diedrich, Yates, Jones: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).

Qiu, Fan, Zhu, Kwan, Chen, Chen, Ying, Zhou, Gu, Wang, Cheng, Zeng, Wan, Mok, Wong, Bao: "KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1." in: Oncotarget, Vol. 6, Issue 31, pp. 31702-20, (2015) (PubMed).

Ratovitski: "Phospho-ΔNp63α/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas." in: Cell cycle (Georgetown, Tex.), Vol. 13, Issue 5, pp. 749-61, (2014) (PubMed).

Walsh, Bolger, Byrne, Cocchiglia, Hao, Fagan, Qin, Cahalin, McCartan, McIlroy, OGaora, Xu, Hill, Young: "Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis." in: Cancer research, Vol. 74, Issue 9, pp. 2533-44, (2014) (PubMed).

Lee, Yang, Park: "Hypoxia enhances the expression of prostate-specific antigen by modifying the quantity and catalytic activity of Jumonji C domain-containing histone demethylases." in: Carcinogenesis, Vol. 34, Issue 12, pp. 2706-15, (2013) (PubMed).

Lu, Ward, Kapoor, Rohle, Turcan, Abdel-Wahab, Edwards, Khanin, Figueroa, Melnick, Wellen, ORourke, Berger, Chan, Levine, Mellinghoff, Thompson: "IDH mutation impairs histone demethylation and results in a block to cell differentiation." in: Nature, Vol. 483, Issue 7390, pp. 474-8, (2012) (PubMed).

Mallette, Mattiroli, Cui, Young, Hendzel, Mer, Sixma, Richard: "RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites." in: The EMBO journal, Vol. 31, Issue 8, pp. 1865-78, (2012) (PubMed).

Luo, Chang, Zhong, Pandey, Semenza: "Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. E3367-76, (2012) (PubMed).

Aliases for KDM4C 抗体

lysine demethylase 4C (KDM4C) 抗体
jumonji domain containing 2c (Jmjd2c) 抗体
lysine demethylase 4C (kdm4c) 抗体
lysine (K)-specific demethylase 4C (Kdm4c) 抗体
lysine demethylase 4C (Kdm4c) 抗体
2410141F18Rik 抗体
AA517467 抗体
bA146B14.1 抗体
GASC1 抗体
Gasc1 抗体
JHDM3C 抗体
JMJD2C 抗体
Jmjd2c 抗体
TDRD14C 抗体
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