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ITPKA 产品

(Inositol-Trisphosphate 3-Kinase A (ITPKA))
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011].

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Featured ITPKA Categories

ITPKA 抗体

High quality antibodies with extensive validation data.

ITPKA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ITPKA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ITPKA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN544977
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258729
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
Cat. No. ABIN7185061
Quantity 100 μg
Datasheet Datasheet

Recommended ITPKA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648249
Quantity 96 tests
Datasheet Datasheet

Recommended ITPKA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3082008
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3126539
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2723916
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our ITPKA Products

González, Schell, Letcher, Veprintsev, Irvine, Williams: "Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase." in: Molecular cell, Vol. 15, Issue 5, pp. 689-701, (2004) (PubMed).

Mishra, Bhalla: "Simulations of inositol phosphate metabolism and its interaction with InsP(3)-mediated calcium release." in: Biophysical journal, Vol. 83, Issue 3, pp. 1298-316, (2002) (PubMed).

Schell, Erneux, Irvine: "Inositol 1,4,5-trisphosphate 3-kinase A associates with F-actin and dendritic spines via its N terminus." in: The Journal of biological chemistry, Vol. 276, Issue 40, pp. 37537-46, (2001) (PubMed).

Synonyms and alternative names related to ITPKA

inositol-trisphosphate 3-kinase A-like (LOC564528), Inositol-trisphosphate 3-kinase A (ip3ka), inositol-trisphosphate 3-kinase A (ITPKA), inositol 1,4,5-trisphosphate 3-kinase A (Itpka), inositol-trisphosphate 3-kinase A (Itpka), IP3-3KA, IP3KA

Protein level used designations for ITPKA

  • 1D-myo-inositol-trisphosphate 3-kinase A
  • Inositol-trisphosphate 3-kinase A
  • IP3 3-kinase A
  • IP3-kinase A
  • IP3K A
  • inositol-trisphosphate 3-kinase A
  • insP 3-kinase A
  • inositol 1,4,5-trisphosphate 3-kinase A
  • inositol 1,4,5-triphosphate 3-kinase
  • inositol 145-triphosphate 3-kinase
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