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ITIH4 产品

(Inter alpha Globulin Inhibitor H4 (ITIH4))
The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].

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Featured ITIH4 Categories

ITIH4 抗体

High quality antibodies with extensive validation data.

ITIH4 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ITIH4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ITIH4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7438337
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7436555
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7438340
Quantity 100 μL
Datasheet Datasheet

Recommended ITIH4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (5)
Cat. No. ABIN6730974
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956863
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6975603
Quantity 96 tests
Datasheet Datasheet

Recommended ITIH4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3082293
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3082294
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130925
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ITIH4 Products

Lee, Yang, Kim, Cha, Lee, Kim, Song, Chun, Seong: "Inter-alpha Inhibitor H4 as a Potential Biomarker Predicting the Treatment Outcomes in Patients with Hepatocellular Carcinoma." in: Cancer research and treatment : official journal of Korean Cancer Association, Vol. 50, Issue 3, pp. 646-657, (2018) (PubMed).

Desoubeaux, Jourdan, Valera, Jardin, Hem, Caille, Cormier, Marchand-Adam, Bailly, Diot, Chandenier: "Proteomic demonstration of the recurrent presence of inter-alpha-inhibitor H4 heavy-chain during aspergillosis induced in an animal model." in: International journal of medical microbiology : IJMM, Vol. 304, Issue 3-4, pp. 327-38, (2014) (PubMed).

van Swelm, Laarakkers, Kooijmans-Otero, de Jong, Masereeuw, Russel: "Biomarkers for methotrexate-induced liver injury: urinary protein profiling of psoriasis patients." in: Toxicology letters, Vol. 221, Issue 3, pp. 219-24, (2013) (PubMed).

Tanaka, Shimazawa, Takata, Kaneko, Tsuruma, Ikeda, Warita, Aoki, Yamada, Takahashi, Hozumi, Minatsu, Inuzuka, Hara: "ITIH4 and Gpx3 are potential biomarkers for amyotrophic lateral sclerosis." in: Journal of neurology, Vol. 260, Issue 7, pp. 1782-97, (2013) (PubMed).

Májek, Reicheltová, Suttnar, Cermák, Dyr: "Plasma protein alterations in the refractory anemia with excess blasts subtype 1 subgroup of myelodysplastic syndrome." in: Proteome science, Vol. 10, Issue 1, pp. 31, (2012) (PubMed).

Májek, Reicheltová, Suttnar, Cermák, Dyr: "Plasma proteome changes associated with refractory cytopenia with multilineage dysplasia." in: Proteome science, Vol. 9, pp. 64, (2011) (PubMed).

Tang, Kitisin, Jogunoori, Li, Deng, Mueller, Ressom, Rashid, He, Mendelson, Jessup, Shetty, Zasloff, Mishra, Reddy, Johnson, Mishra: "Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 7, pp. 2445-50, (2008) (PubMed).

Werbowetski-Ogilvie, Agar, Waldkircher de Oliveira, Faury, Antel, Jabado, Del Maestro: "Isolation of a natural inhibitor of human malignant glial cell invasion: inter alpha-trypsin inhibitor heavy chain 2." in: Cancer research, Vol. 66, Issue 3, pp. 1464-72, (2006) (PubMed).

Zhuo, Hascall, Kimata: "Inter-alpha-trypsin inhibitor, a covalent protein-glycosaminoglycan-protein complex." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38079-82, (2004) (PubMed).

Cuvelier, Muir, Martin, Sesboüé: "[Proteins of the inter-alpha trypsin inhibitor (ITI) family. A major role in the biology of the extracellular matrix]." in: Revue des maladies respiratoires, Vol. 17, Issue 2, pp. 437-46, (2000) (PubMed).

Synonyms and alternative names related to ITIH4

inter alpha-trypsin inhibitor, heavy chain 4 (Itih4), inter-alpha-trypsin inhibitor heavy chain family member 4 (ITIH4), inter-alpha-trypsin inhibitor heavy chain family, member 4 (Itih4), GP120, H4P, IHRP, ITI-HC4, Itih-4, ITIHL1, PK-120, PK120

Protein level used designations for ITIH4

  • ITI heavy chain H4
  • PK-120
  • inter-alpha-inhibitor heavy chain 4
  • inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)
  • inter-alpha-trypsin inhibitor family heavy chain-related protein
  • inter-alpha-trypsin inhibitor heavy chain H4
  • inter-alpha-trypsin inhibitor, heavy chain-like, 1
  • plasma kallikrein-sensitive glycoprotein 120
  • inter alpha-trypsin inhibitor, heavy chain 4
  • inter-alpha-inhibitor H4 heavy chain
  • ITI-HC4
  • MAP
  • major acute phase protein
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