ITM2C 抗体
(Integral Membrane Protein 2C (ITM2C))
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C- terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
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Aliases for ITM2C 抗体
integral membrane protein 2C (Itm2c) 抗体integral membrane protein 2C (ITM2C) 抗体
integral membrane protein 2Cb (itm2cb) 抗体
integral membrane protein 2Ca (itm2ca) 抗体
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