ITM2C 抗体 (AA 33-226) (Fluoro647)
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Quick Overview for ITM2C 抗体 (AA 33-226) (Fluoro647) (ABIN8000251)
抗原
See all ITM2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-226
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原理
- Anti-ITM2C Antibody Fluoro647 Conjugated
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预测反应
- Human ITM2C shares 94.8% amino acid (aa) sequence identity with mouse,rat ITM2C.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ITM2C recombinant protein (Position: E33-D226). Human ITM2C shares 94.8% amino acid (aa) sequence identity with mouse and rat ITM2C.
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亚型
- IgG
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anti-Integral Membrane Protein 2C (ITM2C) (AA 1-230) antibody
ITM2C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 27-55), (N-Term) antibodyITM2C 适用: 人 WB 宿主: 兔 Polyclonal RB36714 unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 101-150) antibodyITM2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- ITM2C (Integral Membrane Protein 2C (ITM2C))
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别名
- ITM2C
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背景
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Background: Integral membrane protein 2C is a protein that in humans is encoded by the ITM2C gene. The Integral membrane protein 2C (ITM2C) is a type II integral transmembrane protein belonging to a family composed of at least two other members, ITM2A and ITM2B. ITM2C, often called transmembrane protein BRI3, is highly expressed in brain tissue. Yeast two-hybrid screen system revealed that BRI3 could interact with beta-secretase beta-amyloid protein converting enzyme (BACE)1 and the microtubule-destabilizing protein SCG10 (STMN2). It may play a role in TNF-induced cell death and neuronal differentiation. BRI3 was found to inhibit the various processing of amyloid precursor protein (APP) by blocking the access of alpha- and beta-secretases to APP, competitive inhibition of APP processing by BRI3 may provide a new approach to Alzheimer disease (AD) therapy and prevention.
Gene Full Name: integral membrane protein 2C
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基因ID
- 81618
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UniProt
- Q9NQX7
抗原
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