This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.[provided by RefSeq, Mar 2009].
Liu, Lin, Shi, Davies, Wagstaff, Tao, Jans: "PKA-site phosphorylation of importin13 regulates its subcellular localization and nuclear transport function." in: The Biochemical journal, Vol. 475, Issue 16, pp. 2699-2712, (2018) (PubMed).
Sakuma, Davila, Malcolm, Kocher, Tonne, Ikeda: "Murine leukemia virus uses NXF1 for nuclear export of spliced and unspliced viral transcripts." in: Journal of virology, Vol. 88, Issue 8, pp. 4069-82, (2014) (PubMed).
Zehorai, Seger: "Beta-like importins mediate the nuclear translocation of mitogen-activated protein kinases." in: Molecular and cellular biology, Vol. 34, Issue 2, pp. 259-70, (2013) (PubMed).