INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A\; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1\; MIM 180680) and U2 (RNU2\; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008].
Tao, Cai, Sampath: "The Integrator subunits function in hematopoiesis by modulating Smad/BMP signaling." in: Development (Cambridge, England), Vol. 136, Issue 16, pp. 2757-65, (2009) (PubMed).