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IPO13 抗体

IPO13 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7115209
发货至: 中国
  • 抗原 See all IPO13 抗体
    IPO13 (Importin 13 (IPO13))
    适用
    • 19
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    克隆类型
    • 18
    多克隆
    标记
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IPO13 antibody is un-conjugated
    应用范围
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    importin 13
    亚型
    IgG
    Top Product
    Discover our top product IPO13 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    IPO13 (Importin 13 (IPO13))
    别名
    IPO13 (IPO13 产品)
    别名
    3R23 antibody, CG 7212 antibody, CG7212 antibody, Dmel\\CG7212 antibody, Imp13 antibody, imp13 antibody, sd-5 antibody, DDBDRAFT_0205767 antibody, DDBDRAFT_0304414 antibody, DDB_0205767 antibody, DDB_0304414 antibody, DDBDRAFT_0191787 antibody, DDBDRAFT_0304413 antibody, DDB_0191787 antibody, DDB_0304413 antibody, IMP13 antibody, KAP13 antibody, LGL2 antibody, RANBP13 antibody, Kap13 antibody, Ranbp13 antibody, Lgl2 antibody, DKFZp459H088 antibody, cadmus antibody, importin 13 antibody, cdm antibody, IPO13 antibody, AFUA_5G08060 antibody, ANI_1_1340034 antibody, AOR_1_1272114 antibody, ipo13B antibody, ipo13A antibody, ipo13 antibody, Ipo13 antibody
    背景
    Synonyms:KIAA0724, RANBP13 Background:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity). Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13.
    分子量
    97kd
    基因ID
    9670
    UniProt
    O94829
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Protein targeting to Nucleus
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