IL12RB2 抗体
(Interleukin 12 Receptor, beta 2 (IL12RB2))
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012].
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60 results :
IL12RB2
适用: 人
WB, ELISA
宿主: 小鼠
Monoclonal
2H6
unconjugated
IL12RB2
适用: 人
WB, IHC, FACS, IHC (p)
宿主: 兔
Polyclonal
unconjugated
IL12RB2
适用: 人
WB, FACS, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
IL12RB2
适用: 小鼠
WB, IHC, IP, ICC
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our IL12RB2 抗体
: "POSH Regulates CD4+ T Cell Differentiation and Survival." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 10, pp. 4003-13, (2016) (PubMed).: "Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 100, (2016) (PubMed).
: "Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis." in: Cytokine, Vol. 73, Issue 1, pp. 36-43, (2015) (PubMed).
: "Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions." in: Journal of virology, Vol. 88, Issue 13, pp. 7474-84, (2014) (PubMed).
: "Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages." in: Nature immunology, Vol. 12, Issue 6, pp. 551-9, (2011) (PubMed).
: "Role of IFN-gamma in Th1 differentiation: IFN-gamma regulates IL-18R alpha expression by preventing the negative effects of IL-4 and by inducing/maintaining IL-12 receptor beta 2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 12, pp. 6165-72, (2002) (PubMed).
: "Differentiation of murine NK cells into distinct subsets based on variable expression of the IL-12R beta 2 subunit." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 9, pp. 4985-93, (2000) (PubMed).
: "IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6221-8, (2000) (PubMed).
: "Role of IL-12 in intrathymic negative selection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 8, pp. 4349-59, (1999) (PubMed).
: "Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits." in: European journal of immunology, Vol. 29, Issue 6, pp. 2007-13, (1999) (PubMed).
Aliases for IL12RB2 抗体
interleukin 12 receptor subunit beta 2 (IL12RB2) 抗体interleukin 12 receptor, beta 2 (Il12rb2) 抗体
interleukin 12 receptor subunit beta 2 (Il12rb2) 抗体
A930027I18Rik 抗体
Ifnm 抗体
IL-12RB2 抗体
IL12RB2 抗体
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