IL-4 蛋白
(Interleukin 4 (IL4))
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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116 results :
IL4
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
IL4
宿主: Cynomolgus
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
IL4
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
IL4
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
IL4
宿主: 小鼠
宿主: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
IL4
宿主: 人
宿主: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
IL4
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
IL4
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95% by SDS-PAGE
SDS, AcA
Active
1 image
IL4
宿主: 人
宿主: Mammalian Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
IL4
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
IL4
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 % as determined by reducing SDS-PAGE.
IL4
宿主: 大鼠
宿主: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE.
Active
IL4
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 85 % as determined by reducing SDS-PAGE.
Latest Publications for our IL-4 蛋白
: "Linoleic acid inhibits in vitro function of human and murine dendritic cells, CD4+T cells and retinal pigment epithelial cells." in: Graefe's archive for clinical and experimental ophthalmology, (2020) (PubMed).: "Decreased expression of A20 is associated with ocular Behcet's disease (BD) but not with Vogt-Koyanagi-Harada (VKH) disease." in: The British journal of ophthalmology, Vol. 102, Issue 8, pp. 1167-1172, (2019) (PubMed).
: "Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease." in: Investigative ophthalmology & visual science, Vol. 59, Issue 11, pp. 4662-4669, (2019) (PubMed).
: "Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells." in: Scientific reports, Vol. 7, Issue 1, pp. 8519, (2019) (PubMed).
: "ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM." in: Frontiers in cellular neuroscience, Vol. 12, pp. 489, (2018) (PubMed).
: "Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model." in: Scientific reports, Vol. 7, pp. 43322, (2018) (PubMed).
: "Hypermethylation of Interferon Regulatory Factor 8 (IRF8) Confers Risk to Vogt-Koyanagi-Harada Disease." in: Scientific reports, Vol. 7, Issue 1, pp. 1007, (2017) (PubMed).
: "Molecular cloning, recombinant expression and characterization of GMCSF from the rhesus monkey, Macaca mulatta." in: Developmental and comparative immunology, Vol. 40, Issue 1, pp. 69-77, (2013) (PubMed).
: "Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+ T cells." in: Journal of leukocyte biology, Vol. 89, Issue 1, pp. 127-36, (2011) (PubMed).
: "A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6011-21, (2009) (PubMed).
Aliases for IL-4 蛋白
interleukin 4 (IL4) 蛋白interleukin 4 (Il4) 蛋白
BCGF-1 蛋白
BCGF1 蛋白
BSF-1 蛋白
BSF1 蛋白
IL-4 蛋白
Il-4 蛋白
IL2 蛋白
IL4 蛋白
Il4e12 蛋白
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